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Evidence of SARS-CoV-2 RNA in an Oropharyngeal Swab Specimen, Milan, Italy, Early December 2019

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  • Evidence of SARS-CoV-2 RNA in an Oropharyngeal Swab Specimen, Milan, Italy, Early December 2019

    Volume 27, Number 2—February 2021
    Research Letter

    Antonella Amendola1, Silvia Bianchi1, Maria Gori, Daniela Colzani, Marta Canuti, Elisa Borghi, Mario C. Raviglione, Gian Vincenzo Zuccotti, and Elisabetta Tanzi

    ...As participants in Italy’s Measles and Rubella Network, a sensitive case-based surveillance system, we observed in Milan during late autumn 2019 cases of suspected measles in patients who eventually tested negative for measles. We therefore retrospectively explored a possible etiologic involvement of SARS-CoV-2 in these non–measles-linked rash cases...

    One oropharyngeal swab specimen tested positive. ..

    This finding is of epidemiologic importance because it expands our knowledge on timing and mapping of the SARS-CoV-2 transmission pathways. Long-term, unrecognized spread of SARS-CoV-2 in northern Italy would help explain, at least in part, the devastating impact and rapid course of the first wave of COVID-19 in Lombardy...

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