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**sharon sanders** · September 3, 2006, 11:37 PM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Sharpe - How reliable are these reports? One million pigs is a huge number even by Chinese standards.

**HenryN** · September 4, 2006, 01:18 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Commentary at

http://www.recombinomics.com/News/09...ine_China.html

**gsgs** · September 4, 2006, 02:30 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

OK, but this is apparantly not bird flu (red skin ?).
Nor does it seem to interact with or relate to birdflu.

Except that it demonstrates how China uses to report
on such things.

**HenryN** · September 4, 2006, 06:04 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Originally posted by gsgs

OK, but this is apparantly not bird flu (red skin ?).
Nor does it seem to interact with or relate to birdflu.

Except that it demonstrates how China uses to report
on such things.

Petechia is a common symptom of H5N1 and 1918 pandemic influenza.

**kent nickell** · September 4, 2006, 07:01 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Very interesting and it may be interesting to see how this ties in with the previously unprecedented report of virulent Streptococcus suis infection in pigs that apparently also killed 39 of 215 human cases. These were evaluated by a panel of WHO experts with data provided by the Chinese Ministry of Health and thought to be compatible with possibly a new and virulent strain of S. suis but asked for continued monitoring and updating.

WHO Western Pacific | World Health Organization

http://www.wpro.who.int/media_centre/news/news_20050816.htm

Promote health. Save lives. Serve the vulnerable.

""Outbreak associated with Streptococcus suis in pigs in China: Update
16 August 2005 - As China moves towards concluding its investigation into the recent outbreak in Sichuan Province associated with Streptococcus suis in pigs, the Ministry of Health of China has shared more details with WHO about the outbreak""

I think it's also worth noting that I believe SARS was also at first thought to be due to a bacterial infection. Either way looks like a serious problem that needs further investigation.

Related articles:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1434494

Streptococcal Toxic Shock Syndrome Caused by Streptococcus suis Serotype 2

Jiaqi Tang,#1* Changjun Wang,#1 Youjun Feng,#2,10 Weizhong Yang,#3 Huaidong Song,#4,9 Zhihai Chen,#5 Hongjie Yu,#3 Xiuzhen Pan,1 Xiaojun Zhou,6 Huaru Wang,1 Bo Wu,6 Haili Wang,1 Huamei Zhao,1 Ying Lin,7 Jianhua Yue,1 Zhenqiang Wu,7 Xiaowei He,7 Feng Gao,2 Abdul Hamid Khan,2,10 Jian Wang,8 Guo-Ping Zhao,9 Yu Wang,3* Xiaoning Wang,7* Zhu Chen,4,9 and George F Gao2*

1Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China , 2Center for Molecular Immunology and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China , 3Chinese Center for Disease Control and Prevention (China CDC), Beijing, China , 4State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Medical School of Shanghai Jiao-Tong University, Shanghai, China , 5Beijing Ditan Hospital, Beijing, China , 6Department of Pathology, Jinling Hospital of Nanjing, Nanjing, China , 7School of Biosciences and Bioengineering, South China University of Technology, Guangzhou, China , 8Beijing Genomics Institute, Chinese Academy of Sciences, Beijing, China , 9Chinese National Human Genome Center, Shanghai, China , 10Graduate School, Chinese Academy of Sciences, Beijing, China

and

| Yale and the World

http://yaleglobal.yale.edu/display.article?id=7518

The Sovereignty of Disease

Outbreaks of infectious disease demand rapid global response for monitoring and protection

David L. Heymann
YaleGlobal, 6 June 2006

**HenryN** · September 4, 2006, 07:27 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

There was considerable debate out release of samples from the 2005 outbreak, which was considerably smaller in scope than the current outbreak.

I am not sure that the samples from 2005 have been released (or independently tested for H5N1).

**Sharpe** · September 4, 2006, 08:04 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Originally posted by Florida1

Sharpe - How reliable are these reports? One million pigs is a huge number even by Chinese standards.

These reports are being posted on Promed--they are being written by Chinese government officials telling pig herders what to do about their dying pigs. They are being written about in Chinese economic journals--because pig prices in China are rising rapidly due to the lack of pigs. I don't know how much more reliable you want them to be. We're not talking about a million pigs. We're probably talking about tens to hundreds of millions of pigs. The same thing has been occurring across the China Sea in the Philippines this summer. So many pigs were dying that they were worried about a scarcity of pigs. GSGS is right that red rashes have not been very prominently described in reports of H5N1 cases, but as Dr. Niman points out, it is a classic sign of DIC--which is what occurs with bird flu--hence the nosebleeds, etc. And if you go back and look at the reports that I typed up from 1918 yesterday, you will see that it was incredibly common for people to have large red rashes.

One thing that I would like to know is simply this: All the deaths that have suddenly occurred due to encephalitis in Henan and Shanxi in the last few weeks--were they pig-herders?

**sharon sanders** · September 4, 2006, 08:32 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Thanks Sharpe.

**sharon sanders** · September 4, 2006, 08:35 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Friday, September 01, 2006
<SCRIPT language=javascript type=text/javascript>if(uid) {document.write('<a href="javascript: window.print();">');}else {document.write('<a href="/users/login.php?redirect=%2Fswinenews%2F12167%2Fchina-piglet-market-weekly%2Fprint&loginrequired=true&por=true">');}</SCRIPT>Print This Page China Piglet Market Weekly

CHINA - In this weeks China Piglet Market Weekly, eFeedLink report that China's piglet prices were stable to higher during the week ending Aug 31.

Price summary

In Hunan province, piglet prices were slightly higher after the pig disease outbreak was brought under control. Market analysis

Key characteristics of China's piglet market during the week under review were as follows:

Farmers' interest in taking up piglet supplies varied from region to region. In the north, farmers were mostly concerned over the possibility of pig diseases which are likely to occur in autumn. Going forward, lower temperatures will also slow the rate of fattening hogs, and this has discouraged some farmers from taking up supplies.

The temperature in southern China's winter will still be higher than those in the north. Other than in the areas affected by pig diseases, farmers' interest in buying piglets are still higher.

In the initial period of the pig disease outbreak, many hogs and sows had succumbed to the disease. Traders and meat processors had thus seized the opportunity to bargain for very low hog procurement prices. This had affected farmers' interest in taking up piglet supplies, and piglet prices were slightly lower even in the unaffected areas during the first half of the week in review.

Earlier, the pig disease had also killed many hogs, especially in farms with big herds in parts of Hunan province. After authorities there had rolled out measures to bring the outbreak under control, piglet replenishment activities had started to recover.

Meanwhile, deliveries of piglets to other regions had also increased. In regions where piglet inventory had been low, farmers were seen more active in taking up piglet supplies.

By making piglet replenishment during this period (late August to September), farmers were hoping to bring in profits early next year as piglets would have fattened sufficiently to be sold as hogs during the Spring Festival (Feb 18) in 2007.

Parts of south-western China continued to be plagued by a dry spell. With temperature hovering around 40 deg C, farmers there were less active in taking up piglet supplies. Market forecast

As measures to control the pig disease takes effect, analysts expect piglet replenishment in regions previously affected by pig disease to pick up.

In the week ahead, piglet replenishment activities are expected to pick up in southern China, while those in the north may not increase much. Overall, piglet prices are seen stable.

http://www.thepigsite.com/swinenews/...-market-weekly

**HenryN** · September 4, 2006, 08:40 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Originally posted by Sharpe

These reports are being posted on Promed--they are being written by Chinese government officials telling pig herders what to do about their dying pigs. They are being written about in Chinese economic journals--because pig prices in China are rising rapidly due to the lack of pigs. I don't know how much more reliable you want them to be. We're not talking about a million pigs. We're probably talking about tens to hundreds of millions of pigs. The same thing has been occurring across the China Sea in the Philippines this summer. So many pigs were dying that they were worried about a scarcity of pigs. GSGS is right that red rashes have not been very prominently described in reports of H5N1 cases, but as Dr. Niman points out, it is a classic sign of DIC--which is what occurs with bird flu--hence the nosebleeds, etc. And if you go back and look at the reports that I typed up from 1918 yesterday, you will see that it was incredibly common for people to have large red rashes.

One thing that I would like to know is simply this: All the deaths that have suddenly occurred due to encephalitis in Henan and Shanxi in the last few weeks--were they pig-herders?

What is left unsaid is frequently more infoprmative than what is said with regard to H5N1 infections. The list of examples is very long (i.e. most H5N1 confirmed index cases for a countriy are clusters and today the 2004 H5N1 infections of dogs in Thailand

H5N1 Canine Deaths in Thailand

http://www.recombinomics.com/news/10040401/canine_deaths.html

Recombinomics Commentary

are being discussed in late 2006 because the Thai governemnt said (in 2004) that the 2004 positives were "mislabeled".

H5N1 Canine Sequence Similar Feline

http://www.recombinomics.com/News/05230602/H5N1_Canine.html

Recombinomics Commentary

In China, the fact that there has been no announced diagnosis on a pig disease that began in June and has spread over a large geographical range in the heart of swine growing territory and has killed 1, 10, or 100 million pigs, speaks volumes.

**Vibrant62** · September 4, 2006, 09:50 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Back in Februrary there were reports of China carrying out a mass cull of dogs in Yunan, officially in a bid to control rabies. I have not been able to find reports of additional dog culls elsewhere, but remember reading several different articles on this, so I beleive it was quite a widespread cull. Given confirmation of H5N1 infected dogs recently and these pig deaths I am wondering if there may be a geographical link between the two incidences, especially as it involves China - which means we must 'watch what they do, not what they say' to glean what is going on.

Does anyone with a better grasp of geography (or ability to find maps electronically) know if the regions with dog culling in China are the same as these mass pig deaths?

**HenryN** · September 4, 2006, 09:53 AM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

Originally posted by Vibrant62

Back in Februrary there were reports of China carrying out a mass cull of dogs in Yunan, officially in a bid to control rabies. I have not been able to find reports of additional dog culls elsewhere, but remember reading several different articles on this, so I beleive it was quite a widespread cull. Given confirmation of H5N1 infected dogs recently and these pig deaths I am wondering if there may be a geographical link between the two incidences, especially as it involves China - which means we must 'watch what they do, not what they say' to glean what is going on.

Does anyone with a better grasp of geography (or ability to find maps electronically) know if the regions with dog culling in China are the same as these mass pig deaths?

The H5N1 dog deaths in Thailand were in 2004 and the culling from rabies was largely limited to a small region (town?) in China.

**Mingus** · September 4, 2006, 02:12 PM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

The circovirus haved cause many problem in north america.
1000000 cases in china, is ... possible given the scale of the epidemic here.

it cause syndromes named PMWS and PDNS.
but many of its complication can be associate with others pathogens

| The Pig Site

http://www.thepigsite.com/articles/1/health-and-welfare/293/disease-focus-pmws-and-pdns-updated-3rd-feb-2001

Skin lesions associated with PMWS and PDNS

Enlarged lymph glands associated with PMWS.

Symptoms

Weaners & Growers

PMWS tends to be a slow and progressive disease with a high fatality rate in affected pigs.
Starting usually at about 6 - 8 weeks of age, weaned pigs lose weight and gradually become emaciated. Their hair becomes rough, their skins become pale and sometimes jaundiced and they are innappetant.
Sudden death.
Enlarged peripheral lymph nodes, particularly in between the back legs. Hold the pig up and you may see the inguinal nodes up to the size of golf balls.
May show diarrhoea in 30% of cases.
Cases of porcine dermatitis nephropathy syndrome (PDNS) are often seen in herds affected with PMWS.
May show respiratory distress or laboured breathing caused by interstitial pneumonia.
Discoloured ears may also be seen.
Incoordination.
Nervous signs may occasionally be seen.
Post weaning mortality is likely to rise to 6 - 10% but is sometimes much higher (20%). In older pigs mortality can rise to 10%.
Clinical cases may keep occurring in a herd over many months. They usually reach a peak after 6 - 12 months and then gradually decline. Numbers affected vary from one group to another.
Growth rates in affected pigs are often normal.
No response to treatment

Sows & Piglets

Mature animals, sows, boars and sucking piglets are not affected and it is uncommon for newly weaned pigs to be affected before 6 weeks of age.

**gsgs** · September 4, 2006, 02:29 PM

Re: CHINA - Unknown disease kills >1,000,000 pigs in 1 district alone

no mention of increased temperature and rapid breathing, though.