Cambodia: 2 new H5N1 cases - Man, 58 - recovered and Girl, 6 - death

[Gert van der Hoek]

02 July 2013|

Six-year-old Cambodian girl dies from bird flu: WHO


HNOM PENH: A six-year-old Cambodian girl has died from bird flu, bringing the country?s toll from the deadly virus to nine so far this year, the World Health Organisation said Tuesday.
The girl, from the southern province of Kampot, died in a children?s hospital in the capital Phnom Penh on June 28, the WHO said in a joint statement with the Cambodian health ministry.
Her death makes it the deadliest outbreak in the kingdom, topping the eight killed by the illness in 2011.


Read more: Six-year-old Cambodian girl dies from bird flu: WHO - Latest - New Straits Times http://www.nst.com.my/latest/six-yea...#ixzz2XtVUxBhR

[Gert van der Hoek]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

Cambodian young girl dies of bird flu

English.news.cn 2013-07-02

PHNOM PENH, July 2 (Xinhua) -- A six-year-old girl from Cambodia 's Southwestern Kampot province died of Avian Influenza H5N1, bringing the death toll to nine and the number of the cases to 13 so far this year, a joint statement by the World Health Organization and Cambodian Health Ministry said Tuesday.

The girl was confirmed positive for human H5N1 avian influenza on Friday last week by the Institut Pasteur du Cambodge, the statement said, adding that she developed fever and headache last Monday and her condition worsened with cough and dyspnea.

The girl was taken to a private clinic until, last Friday, she was admitted to Kantha Bopha Hospital with fever, dyspnea and cough, it said.

"In Kantha Bopha Hospital, the girl was treated with Tamiflu, but died later in the night," it said. "There have been recent poultry deaths in the girl's village and the girl was likely to be exposed to sick and dead poultry before she became sick."

"Avian influenza H5N1 remains a serious threat to the health of all Cambodians. This is the 13th case of H5N1 infection in humans this year," Health Minister Mam Bunheng said in the statement.

He said children also seem to be most vulnerable and are at high risk because they like to play where poultry are found.

"I urge parents and guardians to keep children away from sick or dead poultry and prevent them from playing with chickens and ducks," he said. "Parents and guardians must also make sure children wash their hands with soap and water after any contact with poultry."

H5N1 influenza is a flu that normally spreads between sick poultry, but it can sometimes spread from poultry to humans, the statement said, adding that it is a very serious disease that requires hospitalization.

Cambodia sees the worst outbreak of the virus this year since the disease was first identified in 2004. To date, the country has recorded 34 human cases of the virus, which has killed 28 people.

Globally since 2003, there have been 632 laboratory confirmed human cases of H5N1 avian influenza with 376 related deaths, said the statement.

[sharon sanders]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

"Avian influenza H5N1 remains a serious threat to the health of all Cambodians. This is the 13th case of H5N1 infection in humans this year," Health Minister Mam Bunheng said in the statement.

We have only 12 total cases documented for 2013. So either the health minister mis-spoke or there is another case that still needs to be officially announced.

[Giuseppe]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

[Source: World Health Organization, Regional Office for the Western Pacific, full page: (LINK).]

13th New Human Case of Avian Influenza H5N1 in Cambodia in 2013

Joint news release of the Ministry of Health of the Kingdom of Cambodia and World Health Organization

PHNOM PENH, 2 July 2013


The Ministry of Health (MoH) of the Kingdom of Cambodia wishes to advise members of the public that one more new human case of avian influenza has been confirmed positive for the H5N1 virus. This is 13th case this year and the 34th person to become infected with the H5N1 virus in Cambodia. Of the 34 confirmed cases, 23 were children under 14, and 21 of the 34 were female. In addition, there were only 4 cases out of 13 cases this year survived.

The 13th case, a six-year-old girl from Preyleu village, Bantheay Meas commune, Bantheay Meas district in Kampot province was confirmed positive for human H5N1 avian influenza on 28th June 2013 by Institut Pasteur du Cambodge.

She developed fever and headache on 24th June. On 26th June her condition worsened with cough and dyspnea and she was taken to a private clinic. On 28th June, the girl was admitted to Kantha Bopha Hospital with fever, dyspnea and cough. In Kantha Bopha Hospital, the girl was treated with Tamiflu but died later in the night.

There have been recent poultry deaths in the village and the girl was likely to be exposed to sick and dead poultry before she became sick.

The 11th case, a five-year-old girl from Tep Rom village, Veal Ponn commune, Thpong district in Kampong Speu province tested positive for influenza A (H1N1) on 30 January 2013. After random retrospective re-testing of samples, it was confirmed on 2nd May that the girl was also infected with the H5N1 human avian influenza virus. The girl has recovered.

The 12th case, a 58-year-old man from Sangkat Chroy Chorng Va, Khan Roeusey Keo, Phnom Penh, tested positive for influenza on 9 January 2013. After routine retrospective testing of samples, it was confirmed on 21st June that the man was also co-infected with the H5N1 human avian influenza virus. He was discharged from the Khmer-Soviet Friendship Hospital and has recovered.

"Avian influenza H5N1 remains a serious threat to the health of all Cambodians. This is the 13th case of H5N1 infection in humans this year. Children also seem to be most vulnerable and are at high risk because they like to play where poultry are found. I urge parents and guardians to keep children away from sick or dead poultry and prevent them from playing with chickens and ducks. Parents and guardians must also make sure children wash their hands with soap and water after any contact with poultry. If they have fast or difficult breathing, they should seek medical attention at the nearest health facility and attending physicians must be made aware of any exposure to sick or dead poultry,? said H.E. Dr. Mam Bunheng, Minister of Health.

The Ministry of Health's Rapid Response Teams (RRT) are currently in the village to identify the girl?s close contacts, any epidemiological linkage among the 13 cases and initiate preventive treatment as required. In addition, a public health education campaign is being conducted in the village to inform families on how to protect themselves from contracting avian influenza. The government's message is - wash hands often; keep children away from poultry; keep poultry away from living areas; do not eat dead or sick poultry; and all poultry eaten should be well cooked.

H5N1 influenza is a flu that normally spreads between sick poultry, but it can sometimes spread from poultry to humans. Human H5N1 avian influenza is a very serious disease that requires hospitalization. Although the virus currently does not easily spread among humans, if the virus changes it could easily be spread like seasonal influenza. Hence, early recognition of cases is important.

Globally since 2003, there have been 632 laboratory confirmed human cases of H5N1 avian influenza with 376 related deaths.

The Ministry of Health will continue to keep the public informed of developments via the MoH website www.cdcmoh.gov.kh where relevant health education materials can also be downloaded.

For more information on human influenza please call the MoH Influenza Hotline numbers: 115 (free call); 012 488 981 or 089 669 567

For contact: Ministry of Health of Cambodia, Dr Sok Touch: Tel +855 12 856 848, Dr Ly Sovann: Tel +855 12 825 424 / World Health Organization, Dr Pieter Johannes van Maaren: Tel +855 23 216 610, Dr Reiko Tsuyuokoa: Tel: +855 23 216 610

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[sharon sanders]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

Thanks Guiseppe. That is the first public announcement of the 58 year old man. I will add him to our case charts.

[Biological]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

FAO Empres-i: latest 25 disease events

03/07/2013: Cambodia - Influenza - Avian
03 July 2013, 12:13:20
Confirmed Influenza - Avian in Kampot, for human

http://empres-i.fao.org/empres-i/2/obd?idOutbreak=176531&rss=t

03/07/2013: Cambodia - Influenza - Avian
03 July 2013, 12:13:20
Confirmed Influenza - Avian in Phnom Penh, for human

http://empres-i.fao.org/empres-i/2/obd?idOutbreak=176530&rss=t

[alert]

Re: Cambodia: six-year-old girl dies from bird flu: WHO

[Source: World Health Organization, Regional Office for the Western Pacific, full page: (LINK).]

The 11th case, a five-year-old girl from Tep Rom village, Veal Ponn commune, Thpong district in Kampong Speu province tested positive for influenza A (H1N1) on 30 January 2013. After random retrospective re-testing of samples, it was confirmed on 2nd May that the girl was also infected with the H5N1 human avian influenza virus. The girl has recovered.

The 12th case, a 58-year-old man from Sangkat Chroy Chorng Va, Khan Roeusey Keo, Phnom Penh, tested positive for influenza on 9 January 2013. After routine retrospective testing of samples, it was confirmed on 21st June that the man was also co-infected with the H5N1 human avian influenza virus. He was discharged from the Khmer-Soviet Friendship Hospital and has recovered.
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Is this the first (accurate) report from anywhere in the world of H1N1 and H5N1 co-infections? I hope they have sequenced the viruses and confirmed that no reassortment has taken place.

And the phrase "human avian influenza virus" in the absence of a machine translator is a bad sign. Avian influenza by definition is not a human virus. This could just be an awkward way of saying "human infection with an avian influenza virus", but still...

[Giuseppe]

Re: Cambodia: 2 new H5N1 cases - Man, 58 - recovered and Girl, 6 - death

Of interest, also, the fact that both co-infected patients survived illness where almost all other H5N1 Cambodian patients died.

Did Heterotypic immunity or N1-antibody response play a role?