Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses, 25 May 2013 (WHO, May 27 2013, edited)

[Giuseppe]

[Source: World Health Organization, full PDF document: (LINK). Edited.]


Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses, 25 May 2013


[Parent virus - Candidate vaccine virus - Type of virus or reassortant - Developing institute - Available from]

• A/Shanghai/2/2013, Synthetic HA&NA
  • IDCDC-RG32A* - Reverse genetics - CDC, USA - CDC, USA
  • NIBRG-267** - Reverse genetics - NIBSC, UK - NIBSC, UK
  • CBER-RG4A** - Reverse genetics - CBER, USA - CBER, USA
• A/Anhui/1/2013
  • Wild type virus ? ? ? ? - WHO CCs
  • NIBRG-268* - Reverse genetics - NIBSC, UK - NIBSC, UK

(*) These viruses are candidate vaccine viruses which have passed relevant safety testing and two-way haemagglutination inhibition (HI) tests. They can be handled under BSL-2 enhanced containment(1).

(**) These are potential candidate vaccine viruses which have passed relevant safety testing and can be handled under BSL-2 enhanced containment(1). Full virus characterization is yet to be finished.


Institutes contact details for candidate vaccine viruses orders/information:

• CBER: Zhiping.Ye@fda.hhs.gov
• CDC: rvd6@cdc.gov
• NIBSC: standards@nibsc.hpa.org.uk or enquiries@nibsc.hpa.org.uk
• WHO CCs: http://www.who.int/influenza/gisrs_laboratory/collaborating_centres/list/en/

For general enquiries, please contact gisrs-whohq@who.int

For other candidate vaccine viruses and potency testing reagents, please go to http://www.who.int/influenza/vaccines/virus/candidates_reagents/home/
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(1) http://www.who.int/biologicals/areas/vaccines/influenza/biosafety_risk_assessment_10may2013.pdf


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