China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

[Pathfinder]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Translation Google

Ministry of Agriculture: a total of 46 positive samples of avian influenza found no pigs infected

Published :2013-4-27 10:02:00
　　
BEIJING, April 26 message, according to the website of the Ministry of Agriculture, as of April 26, the provinces and the National Avian Influenza Reference Laboratory were found 46 positive H7N9 avian influenza virus, not isolated H7N9 avian influenza from poultry farms around virus, also found no pigs infected with the virus.
　　
Ministry of Agriculture said that as of April 26, the provinces and the National Avian Influenza Reference Laboratory samples 390628, the sample covers 13,014 monitoring sampling field point, of which 2,587 live poultry market, 337 poultry slaughterhouse, 8808 poultry farm (village), 341 wild birds habitat, 277 pig slaughterhouse, 31 pig farms and 633 environmental sampling point.
　　
Present, were detected in samples of 218,897 copies, which serological 150,837 samples, 68060 etiology samples. 68060 etiology samples found that 46 H7N9 avian influenza virus, the positive rate of 0.07%. 44 of 14 from Shanghai, Anhui, Zhejiang, Jiangsu and Henan provinces (municipalities) of live poultry business market (points) poultry and environmental samples; 2 positive samples from pigeons, Nanjing, Jiangsu Province samples from MSC County, Nantong City, Jiangsu Province, Pigeon farmers. The remaining samples were negative. Up to now, all over is not isolated from poultry farms to the H7N9 avian influenza virus, also found no pigs infected with the virus.
　　
Next, the Ministry of Agriculture will continue to strengthen the sector, in close collaboration to strengthen the linkage. The same time, to further strengthen the monitoring of H7N9 avian influenza virus, strengthen the study of the characteristics of the virus and dissemination of law, to carry out risk assessment and situation judged, effective and orderly and effective good response.

(China News Network)

http://www.99sj.com/News/256597.htm

[Shiloh]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Source: http://news.dayoo.com/china/57400/20..._110021628.htm

Zhejiang Yiwu market chicken samples the H7N9 positive for the city to stop live animal
http://www.dayoo.com/ 2013-04-29 19:45 Source: Zhejiang Online Reviews (0)

Two nights ago, the Ministry of Agriculture Information Office published a news release bar on its official website epidemic: the Ministry of Agriculture to 3 copies of H7N9 avian influenza positive samples detected from samples of Henan and Zhejiang.

The message: Zhejiang animal disease prevention and control center for inspection suspected positive samples for review by the National Avian Influenza Reference Laboratory, were positive for H7N9 avian influenza, samples were collected from the vegetable market, Yiwu, Jinhua, Zhejiang, Chian chicken.

Visit Chi'an farms

Sampling the the chicken samples H7N9 avian influenza-positive vegetable market, opposite the town of Yiwu Chian benefits of hotel, the locals like to call it the "village vegetable market.

Yesterday afternoon, coming and going, the market is no different with the past.

Fish Zhang, Jiangxi, a few months ago, first came to the vegetable market. For avian influenza things, he was not quite "cold." "At first pass, quite evil, and now, you see, I am in the markets every day, the body is very good."

Zhang opposite the fish stalls, separated by 3 meters, is the problem chicken stalls has been plastic film around it. Through the cracks, I saw inside stacked eight cages, the booth one side there is a stove is used to boil water for the chicken ham hair. Stalls outside the ground, but also keep a lot of the disinfection white powder.

April 16, initially detected the chicken samples H7N9 avian influenza positive, chicken stalls closed.

In the vegetable market, I found a stall she had got, "April 15, someone sample testing results the next day, people come to me about the chicken away. Those days no business almost 10 chickens, eight were taken away. "(Ms. Zhou's memory may deviate According to the records of the relevant departments, the day a total of 12 chickens, 10 of which were taken away processing.)

Zhou said, later also to do a physical examination. "I heard them say, no problem, we can rest assured."

The past few days, the town hospitals doctors every day to the market. Morning Afternoon of all time, to all business operators body temperature, until now, did not find anything. "

Chen Big Brother come to buy vegetables market every day to do the disinfection work, coupled with the chickens, ducks and other poultry is no longer sold, they come here to buy food, do not worry about infection.

It is understood that, as the H7N9 avian flu was first detected positive town in Yiwu, Chian first suspended all poultry trading activities.

Yiwu CDC:

Found no human infection with the H7N9 avian influenza

Yesterday, I went to the the Yiwu CDC.

Yiwu has found no human infection with the H7N9 avian influenza? The Yiwu Communicable Disease Prevention chief Dong Xuanjun first talked about this problem.

"Up to now, Yiwu, the city found no human infection with the H7N9 avian influenza." DONG Xuan Jun said that starting in early April, Yiwu CDC weekly collected by Yiwu Central Hospital more than 15 cases of ordinary flu H7N9 avian influenza virus detection, so far found no suspicious circumstances.

The Dong Xuanjun, while meeting the needs in a timely manner to the case of four categories, Yiwu Central Hospital of human infection with the H7N9 avian influenza virus detection. "The recent history of poultry exposure; temperature greater than or equal to 38 degrees Celsius; flu-like symptoms; leukocyte or lower."

"If people have the above four cases, can go to the nearest community health service centers or Yiwu human infection with the H7N9 avian influenza sentinel clinics hospital Yiwu Central Hospital patient treatment of fever, the fever clinic doctor according to your actual situation to determine need to detect from April 12, has been on the medical staff of the city's medical and health units and private out-patient units in batches training. "

For the consumption of poultry products, DONG Xuan Army gives his own views. 65 degrees 30 minutes inactivated H7N9 avian influenza virus in the environment of 100 degrees Celsius, as long as two minutes can be inactivated, therefore, is not to say that poultry products can not eat, but special attention, Recently consumption poultry food to be cooked fully cooked. "

Livestock sector: Pause live animal

April 23, Yiwu municipal government issued an emergency notice requirements towns Street and the relevant government departments to immediately implement the measures: suspension of live poultry trading; further expand the scope of monitoring; suspension of live poultry transported; carry out illegal feeding of birds culled .

Yesterday, Yiwu Husbandry and Veterinary Bureau staff said: they have strict accordance with the Ministry of Agriculture, Animal H7N9 avian influenza emergency response Guide (Trial) "requirement the Chian vegetable market and remain live chickens sound processing, and venues strict disinfection, a citywide dragnet investigation of the outbreak and epidemiological investigation, starting from April 14, sampling a total of 1200 samples, except Chian, all testing qualified.

Slaughterhouses, markets, farms, three groups of sampling and monitoring work, the moment did not stop, April 23, the city stop live animal, we go to the farms, supervision, is still illegal sales immediately harmless treatment, disinfection work did not do a good job in a timely manner, we immediately notify the relevant departments, to protect the security market. "

H7N9 avian flu suddenly to the livestock industry in Yiwu was injured. In the prevention and control of avian infection at the same time, in order not to let the whole industry collapse, according to the relevant policies in the province, Yiwu livestock sector also strengthened the industry support.

Avian field, each 15 yuan subsidy, the leading enterprises acquired a chicken subsidy, other farms according to size, has also been given compensation policies. "Chen Binfeng

[AlaskaDenise]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Agreed with comments above.

If the farms from whence the chickens (and presumably other poultry) came do not have infection, then the poultry must be getting infected at the wet markets themselves.

So how are they getting infected?...........

From infected (including asymptomatic) vendors?

.

[NS1]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

From infected (including asymptomatic) vendors?

.

Unlocking
a
3 Piece 4D Puzzle

Existence of Keys to Emergent H7N9

A sub-clinical disease pattern in most host subjects of emergent H7N9 with low-to-no morbidity allows "silent spread" between the 3 vector classes with the various mammal species being the most important vector at this time. The genetic evidence presented on this thread and these forums should guide lab heads to task principal investigators with re-examining conventional conclusions about sub-segment viral interchange between terrestrial birds (primarily commercial poultry), mammals (people, canines, felines, mink, seals and whales) and roving birds (anseriformes and passerine).

Historical Method of Reservoir Identification

The emergent H7N9 dynamic may appear unusual in the area of pinpointing a reservoir, but is, in fact, no more unusual than the emergent 2009 H1N1 pandemic where no valid cornerstone reservoir was ever defined, though the public has been consistently led to believe the disease originated in swine. Effort has been expended at every level of virology, extensive effort, to validate the conventional science assumption of swine as the 2009 pandemic base.

More than 7,000 H1 swine sequences appear in the database today with 5,800 after 2004 and 4,900 since 2008. More swine sequences are on file for H1 serotypes than all H5 sequences of all species combined and 3 times the number of all H7 sequences for all species combined.

This costly pursuit of their assumption has not returned a positive finding, but has been prosecuted to adverse effect for surveillance on more probable subjects. The idea that science can conclude so rapidly on a complex problem with diminishing support data and with readily available confounding information defies the very concept of science, of knowledge discovery. This vehement adherence to traditional conclusions, nothing more than blind faith in practice, has no place in disease investigation.

Footing for H7N9 Emergence

The world entered this emergency with a toolkit built around the vast observational database for H7N9 of 26 sequences with analytic-limiting geographic and temporal dispersion (only 6 with 8 complete segments). Today, 4 weeks after announcement of a potential pandemic and 8 weeks after confirmed cases, a total of 15 H7N9 genomes are on file with 8 complete segments (47 HA, 36 HA+NA) and 2 of those are unacknowledged and unannotated practical duplicates with conflicting metadata.

Understanding the disease and preventing potential spread to 1.6 billion people (25% CAR) hinges on a count of pathogen specimens produced by the stellar international virology labs loitering at a population slightly higher than a baker's dozen box of doughnuts.

That's neither good eating, nor sufficient fuel for analysis. Confidence is not generally inspired by those striking so limited a foundation. Perhaps more remains to be understood concerning the initiation, development and maturation of pandemic virus reservoirs. And then again, perhaps the data is of no import to this matter:

Dys-Contiguous emergence in Hunan province was predicted on the 14th of April using the aforementioned limited genetic database. Yesterday, emergence was verified in Hunan as early as April 14th on a positive test confirmation.

System Dynamics of Vector Classes

Complex interplay exists between the three vector classes. Bi-directional transmission will eventually be understood at each level using the proper necropsy procedures and with revision of human testing sensitivity.

• Poultry incubates (chicken, duck with emphases on quail, chukkar, partridge & ratite)
• People incubate (male /female, both tails of the age-to-population curve: very young and very old)
• Passerines incubate and transport over distance (magpies, crows, jays, martins, swallows with emphases on pets & pigeons).

Emergent H7N9 with the proven movement of genetic data involving common passerines may appear daunting and fall outside standing models now, but the ΣH7N9 may be found at some point in the future to be using a very normal form of step-wise genetic acquisition for a pandemic goal-seeking organism. But we may never know because new models arise from data and H7N9 data is sparse geographically, sparse temporally and austerely sparse in every area but sparsity.

Exchange Proposal: Keys For Data

We'd like to propose an exchange: keys for data.

Participants are invited to explore anywhere you want with whatever vehicle you can start with these keys (Open Access, Full Text). Just report back what you find on your trek (GISAID with any ethical clinicals in any language). We've asked for specific data on many previous occasions and have offered the keys as well, but we'll give it another try:

Passerines: Pets & Pigeons
3P's of the emergent H7N9 Puzzle
These 3P's are not dissimilar to 3 keys.

Summary of RFI

One puzzle, four dimensions, three keys . . . all that's missing is one bright lab head. Who will invest the fourth dimension, take these keys, wrinkle the fabric and approach the puzzle?

[kiwibird]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

From infected (including asymptomatic) vendors?

.

Mmm People or p..flies should maybe added to that list!

[Laidback Al]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

The image below is based on information in Post #19 above.


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[NS1]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

That's a great image, Al!

We should have been more specific in our introduction of the idea on this thread.

A great deal of backing data is found on the standard GeneWurx RnR Analytic Summary entitled Cross Serotype Homology covering the first and second human sequence deposits at GISAID. Although the graphic does illustrate, in general, what we believe is a valid permutable set, our comments on this thread were intended to be much more specific toward a proposed mechanism driving the development of the emergent H7N9 Hemagglutinin via accumulative sub-segment genetic transfer from a number of different serotypes in two separate classes of influenza over a time duration of at least 4 years and potentially 11 years.

Let's bring the diagram title into that discussion when you have a moment.

[sharon sanders]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

I am not a genetics expert but it seems to me that if H7N9 is an avian influenza that is fairly well adapted to mammals (as proven by sequence analysis), it must have cycled through swine. Swine are mammals and could be responsible for the mammalian adaptation - which indicates to me that this flu is widespread on pig farms.

The MOA mentioned this possibility in their paper published online yesterday:

"Thirdly, beyond that the virus can infect humans and birds, we think that the virus can also infect pigs which support circulation of both AIVs and human influenza viruses."

http://link.springer.com/content/pdf/10.1007&#37;2Fs11434-013-5880-5.pdf

[gsgs]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

the mammalean adaption had been exaggerated.
It's just those 2 "mammalean" mutations.
We had seen them before in birds.
It was just surprising to see them just after
the Fouchier-Kawaoka predictions.

The virus is still avian since decades.

[Pathfinder]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

French Institute for Public Health
Weekly International Bulletin No. 397 April 24 to 29, 2013

04/30/2013

Translation Google

Excerpt:

The source of contamination and / or exposure factors remain unsolved.

http://www.invs.sante.fr/Publications-et-outils/Bulletin-hebdomadaire-international/Tous-les-numeros/2013/Bulletin-hebdomadaire-international-du-24-au-29-avril-2013.-N-397

http://www.flutrackers.com/forum/showthread.php?t=202845

[kiwibird]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Ministry of Agriculture: avian influenza prevention and control practices worthy of promotion
May 2, 2013 09:12:49 Hangzhou Network Views: 64
Ministry of Agriculture, the World Organization for Animal Health (038) consisting of animal H7N9 avian influenza prevention and control of the joint mission arrived in the city, a two-day inspection in Shanghai. On the morning of April 26, Shanghai Municipal Agricultural Commission briefed the Expedition animal H7N9 avian flu prevention and control work, monitoring and sampling, laboratory testing and market traceability topic for the exchange and discussion. In the afternoon of April 26, the study group also inspected the wholesale market Sanguantang eggs, City animal disease prevention and control center laboratory.
.....Designated road crossing inspection and non-designated crossing inspections and found no live poultry transport vehicles.
April 26, the city animal disease prevention and control center 560 samples were collected, and samples of avian influenza virus nucleic acid detection, results were negative.
Source: Xinmin Evening News Editor: Zouzhuo Qi

Source: http://translate.google.com/translat...new_63401.html (machine translation)


From another thread - prevention info-
Good indoor and outdoor sanitation, garbage removal, elimination of flies, mosquitoes, rats, cockroaches likely to spread disease vectors. Disinfection and hygiene of the pet home, when they go out as much as possible to reduce livestock unnecessary contact.

http://www.flutrackers.com/forum/showthread.php?t=205015

[Ronan Kelly]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Ministry of Agriculture, Shandong, Jiangxi and Guangdong samples detected of 5 H7N9 avian influenza-positive sample
Date :2013-05-05 17:10 Author: Source: Ministry of Agriculture Information Office

　　Information Office of the Ministry of Agriculture released on May 5, the National Avian Influenza Reference Laboratory report detected in environmental samples were positive for the H7N9 avian influenza in Shandong collected 412 samples from Zaozhuang City, Shandong Province, Xingfu Road market. Suspected positive samples Jiangxi animal disease prevention and control center for inspection by the National Avian Influenza Reference Laboratory review, were positive for H7N9 avian influenza, chicken samples from a business point of Nanchang, Jiangxi Province, Nanchang County to the Town. Guangdong provincial animal disease prevention and control center for inspection of a suspected positive samples for review by the National Avian Influenza Reference Laboratory were positive for the H7N9 avian influenza, chicken samples from Dongcheng, Dongguan City, Guangdong Province, three birds wholesale market. Gene sequence analysis showed that all isolates of the H7N9 avian influenza virus strains isolated from pigeons and April 4 highly homologous.

　　Ministry of Agriculture has asked the Shandong Province, Jiangxi Province, Guangdong Province, in strict accordance with the Ministry of Agriculture, Animal H7N9 avian influenza emergency response guide (Trial) "do a good job related to disposal. At the same time to further strengthen the H7N9 avian influenza virus monitoring the effective implementation of prevention and control measures.

　　Up to now, the National Avian Influenza Reference Laboratory detected a total of 51 H7N9 avian influenza positive samples.

http://www.moa.gov.cn/zwllm/zwdt/201305/t20130505_3450918.htm

[Ronan Kelly]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

machine translated;

Ministry of Agriculture from Fujian samples detected an H7N9 avian influenza positive samples
Date :2013-05-09 16:57 Author: Source: Ministry of Agriculture Information Office

　　Information Office of the Ministry of Agriculture released on May 9, National Avian Influenza Reference Laboratory report environmental samples were positive for the H7N9 avian influenza detected in 686 samples collected in Fujian, Fuzhou, Fujian Fuqing City, a small North market. Gene sequence analysis showed that isolates of the H7N9 avian influenza virus strains isolated from pigeons and April 4 highly homologous.

　　Ministry of Agriculture has asked the Fujian Province in strict accordance with the Ministry of Agriculture, Animal H7N9 avian influenza emergency response Guide (Trial) "do a good job related to disposal. At the same time to further strengthen the H7N9 avian influenza virus monitoring the effective implementation of prevention and control measures.

　　Up to now, the National Avian Influenza Reference Laboratory detected a total of 52 H7N9 avian influenza positive samples.

http://www.moa.gov.cn/zwllm/zwdt/201305/t20130509_3456183.htm

[Pathfinder]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Translation Google

Experts reported that live poultry farms H7N9 is likely to be the source of infection

On May 19, 2013 09:59Source: World Wide Web

Released Monday by the Xinhua News Agency, Beijing, May 18 - National Health and Family Planning Commission of China - World Health Organization of human infection with the H7N9 avian influenza prevention and control of joint study group to examine the report pointed out that the live poultry farms is likely to be H7N9 infection source.
　　
By the invitation of the Chinese Ministry of Health and Family Planning Commission, the World Health Organization convened influenza epidemiology, virology, clinical and international experts in the field of Chinese experts together to form a joint study group recently to inspect the Chinese people infected with the H7N9 avian flu situation assessment and completed this inspection report.
　　
The report found around the live bird markets in Shanghai H7N9 bird flu H7N9 virus, a large number of cases have a history of exposure to live or live poultry market, close the live bird markets descendants of infection the number of cases decreased significantly. These tips, live poultry exposure of human infection with the H7N9 avian influenza virus of the key risk factors.
　　
Although the live poultry farms have not found the virus, but they are likely to be the source of infection where the virus is then in the live poultry market continues to expand, leading to human infection. Although still under investigation early stages of limited data, but it appears that due to the inter and intra provincial trade of live poultry, the H7N9 avian influenza virus will continue to exist. The poultry infection can not be controlled, the virus may spread to other provinces in China, leading to the threat of zoonotic increase, thereby enhancing the outbreak evolved into the possibility of an influenza pandemic.
　　
The report, to date, virology is still very limited, but found by gene sequencing of human infection with the virus and virus infection in poultry, this H7N9 avian influenza virus has been adjusted or have the ability to infect humans .

http://news.sohu.com/20130519/n376389206.shtml

[Pathfinder]

Re: China - H7N9 found in chickens says Harbin Veterinary Research Institute: wet markets and farms

Translation Google

Animal H7N9 avian influenza surveillance sampling and laboratory testing has been completed

At 8:57 on May 24, 2013 Source: Economic Times　participate in interactive ( 0 ) 0

Human infection with H7N9 avian influenza occurred since the veterinary departments at all levels actively carried out in accordance with the request of the Ministry of Agriculture monitoring, current monitoring sampling and laboratory testing work has been basically completed.

As of May 22, the national veterinary laboratories were detected at all levels to complete 899,758 samples, covering 31 provinces and the Xinjiang Production and Construction Corps 42,250 monitoring sampling field point. No country was isolated from poultry farms H7N9 avian influenza virus, also found no pigs infected with the virus.

Expert analysis, monitoring results from the current look, from the country more than 30,000 samples of poultry farms all test results were negative and 53 positive samples, 51 were from the live poultry business field point, accounting for 96%. Experts believe that the live animal markets and poultry virus infection is a major source of risk, the current focus on prevention and control of poultry farms is still protected to prevent contamination by the virus. Reporter Qiao Jinliang

http://www.chinanews.com/jk/2013/05-24/4851614.shtml