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Emerg Infect Dis. Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

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  • Emerg Infect Dis. Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

    Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009 (Emerg Infect Dis., abstract, edited)


    [Source: US Centers for Disease Control and Prevention, Emerging Infectious Diseases Journal, full PDF Document (LINK). Edited.]

    DOI: 10.3201/eid1610.100108

    Suggested citation for this article: Keynan Y, Juno J, Meyers A, Ball TB, Kumar A, Rubinstein E, et al. Chemokine receptor 5 Δ32 allele in patients with severe pandemic (H1N1) 2009. Emerg Infect Dis. 2010 Oct; [Epub ahead of print]

    Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

    Yoav Keynan,1 Jennifer Juno,1 Adrienne Meyers, T. Blake Ball, Anand Kumar, Ethan Rubinstein, and Keith R. Fowke
    Author affiliations: University of Manitoba, Winnipeg, Manitoba, Canada (Y. Keynan, J. Juno, A. Meyers, T.B. Ball, A. Kumar, E. Rubinstein, K.R. Fowke); and Public Health Agency of Canada, Winnipeg (A. Meyers, T.B. Ball)
    1These authors contributed equally to this article.


    Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.

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