Viral mechanisms

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Pathogenicity & virulence status

Topics: 2,678 Posts: 2,935

Last Post: Nat Commun . Influenza coinfection inhibits control of mycobacterial infection in a human challenge model

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2,935

Nat Commun . Influenza coinfection inhibits control of mycobacterial infection in a human challenge model

by tetano

Yesterday, 03:34 AM

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Immune response (26/60)	Host binding ability (226/279)	Viral shedding (146/156)
Cytopathogenic effects with balance of replication & host contro (139/143)	Immunosurveillance escape via antigenic variation from immune response (35/35)	Immunosurveillance escape via recombination with different strains from zoonotic disease (2/2)

Tracking nucleotide sequences

Topics: 73 Posts: 171

Last Post: Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

171

Nat Commun . Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift

by tetano

December 13, 2025, 03:04 AM

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HA RBS (9/10)	HA - cleavage (3/62)	NA (7/7)
PB2 (11/34)	M gene (2/2)	M2 (5/5)
NS1 gene (10/10)

PB2 Information

Topics: 58 Posts: 84

Last Post: Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

Nat Commun . The influenza virus PB2 protein evades antiviral innate immunity by inhibiting JAK1/STAT signalling

by tetano

October 26, 2022, 02:19 AM

NS1 Information

Topics: 265 Posts: 279

Last Post: J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

265

279

J Virol . Host-specific functional evolution of seal influenza A virus NS1 protein following avian-to-seal transmission

by tetano

March 27, 2026, 03:52 AM

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J Virol . Gga-miR-92-targeted TNFRSF1B inhibits the replication of influenza A virus by degrading TRAF3 by tetano Started by tetano, Yesterday, 03:29 AM	0 responses 7 views 0 likes	Last Post by tetano Yesterday, 03:29 AM
FASEB J . TurboID-Based Proximity Labeling Map Reveals the Protein Interaction Network and Anti-Viral Mechanism Against Influenza A H1N1 by tetano Started by tetano, June 5, 2026, 11:59 PM	0 responses 13 views 0 likes	Last Post by tetano June 5, 2026, 11:59 PM
J Virol . Rab11B is required for binding and entry of recent H3N2, but not H1N1, influenza A isolates by tetano Started by tetano, June 3, 2026, 01:27 AM	0 responses 19 views 0 likes	Last Post by tetano June 3, 2026, 01:27 AM
Virol J . The activation of the metabolic oxaloacetate-pyruvate axis restores influenza A virus replication during impaired glycolysis by tetano Started by tetano, May 27, 2026, 12:24 AM	0 responses 10 views 0 likes	Last Post by tetano May 27, 2026, 12:24 AM
PLoS One . Computational biology exposed a common pathogenic mechanism in influenza A and Guillain-Barré syndrome by tetano Started by tetano, May 23, 2026, 12:46 AM	0 responses 21 views 0 likes	Last Post by tetano May 23, 2026, 12:46 AM
J Virol . Cellular hnRNP D promotes influenza A virus replication by inhibiting TBK1-IRF3-mediated innate immune response by tetano Started by tetano, May 16, 2026, 01:46 AM	0 responses 18 views 0 likes	Last Post by tetano May 16, 2026, 01:46 AM
Nat Commun . Filamentous morphology of influenza A virus confers enhanced stability in aerosols by tetano Started by tetano, May 16, 2026, 12:47 AM	0 responses 19 views 0 likes	Last Post by tetano May 16, 2026, 12:47 AM
Am J Respir Cell Mol Biol . Recurrent H1N1 Influenza A virus infections cause airway hyperinnervation and cough hypersensitivity via the IFN-γ-JAK-ERK1/2-CDK5 pathway by tetano Started by tetano, May 9, 2026, 02:48 AM	0 responses 26 views 0 likes	Last Post by tetano May 9, 2026, 02:48 AM
Nat Commun . TRIM5 integrates hypoglycemic stress and influenza infection by tetano Started by tetano, May 6, 2026, 01:18 AM	0 responses 24 views 0 likes	Last Post by tetano May 6, 2026, 01:18 AM
Cell Rep . Ubiquilin1 restricts influenza viral replication through trapping vRNP in the late endosomes by tetano Started by tetano, April 29, 2026, 02:17 AM	0 responses 26 views 0 likes	Last Post by tetano April 29, 2026, 02:17 AM

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