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WHO - Human T-lymphotropic virus type 1

Mary Wilson

Well-known member
29 June 2023

Key facts
  • The human T-lymphotropic virus type 1 is also known by the acronym HTLV-1, or as human T-cell leukaemia virus type 1.
  • The virus can cause a type of cancer called adult T-cell leukaemia/lymphoma (ATL).
  • HTLV-1 is transmitted primarily through infected bodily fluids including blood, breast milk and semen.
  • Risk factors include unprotected sex, injecting drug use and transplantation of tissue, blood and blood products.
  • An estimated 5–10 million people globally are infected with HTLV-1, although that number is probably higher due to a lack of reliable data.
Overview

The human T-lymphotropic virus type 1 (HTLV-1) was the first oncogenic human retrovirus to be discovered. It was first studied in 1977. The virus can cause adult T-cell leukaemia/lymphoma (ATL) and progressive nervous system condition known as HTLV-1-associated myelopathy or tropical spastic paraparesis (HAM/TSP).

The current best estimates for the total number of people living with HTLV-1 infection range from 5 million to 10 million. The scarcity of reliable data indicates that is likely an underestimation of actual global numbers.

Transmission

HTLV-1 is understood to be transmitted primarily through direct contact via cell-containing bodily fluids including blood, breast milk and semen. Transmission via direct contact is also considered feasible, although the virus usually exists in the intra-cellular form. ...

https://www.who.int/news-room/fact-sheets/detail/human-t-lymphotropic-virus-type-1

 
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