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Virus Res . Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated

tetano

Editor, Senior Moderator
Virus Res


. 2020 Nov 20;198233.
doi: 10.1016/j.virusres.2020.198233. Online ahead of print.
Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a


Khajohn Joonlasak[SUP] 1 [/SUP], Elizabeth M Batty[SUP] 2 [/SUP], Theerarat Kochakarn[SUP] 3 [/SUP], Bhakbhoom Panthan[SUP] 4 [/SUP], Krittikorn K?mpornsin[SUP] 5 [/SUP], Poramate Jiaranai[SUP] 4 [/SUP], Arporn Wangwiwatsin[SUP] 6 [/SUP], Angkana Huang[SUP] 1 [/SUP], Namfon Kotanan[SUP] 7 [/SUP], Peera Jaru-Ampornpan[SUP] 8 [/SUP], Wudtichai Manasatienkij[SUP] 1 [/SUP], Treewat Watthanachockchai[SUP] 9 [/SUP], Kingkan Rakmanee[SUP] 9 [/SUP], Anthony R Jones[SUP] 1 [/SUP], Stefan Fernandez[SUP] 1 [/SUP], Insee Sensorn[SUP] 4 [/SUP], Somnuek Sungkanuparph[SUP] 10 [/SUP], Ekawat Pasomsub[SUP] 11 [/SUP], Chonticha Klungthong[SUP] 1 [/SUP], Thanat Chookajorn[SUP] 12 [/SUP], Wasun Chantratita[SUP] 13 [/SUP]



Affiliations

Abstract

Coronavirus Disease 2019 (COVID-19) is a global public health threat. Genomic surveillance of SARS-CoV-2 was implemented in March of 2020 at a major diagnostic hub in Bangkok, Thailand. Several virus lineages supposedly originated in many countries were found, and a Thai-specific lineage, designated A/Thai-1, has expanded to be predominant in Thailand. A virus sample in the SARS-CoV-2 A/Thai-1 lineage contains a frame-shift deletion at ORF7a, encoding a putative host antagonizing factor of the virus.

Keywords: COVID-19; Genomic Surveillance; SARS-CoV-2; Thailand.
 
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