tetano
Editor, Senior Moderator
Virol J
. 2024 Nov 13;21(1):291.
doi: 10.1186/s12985-024-02560-2. Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh
L Carnegie[SUP] #[/SUP][SUP] 1 [/SUP], J T McCrone[SUP] 2 3 [/SUP], L du Plessis[SUP] 4 5 [/SUP], M Hasan[SUP] 6 [/SUP], M Z Ali[SUP] 6 [/SUP], R Begum[SUP] 6 [/SUP], M Z Hassan[SUP] 6 [/SUP], S Islam[SUP] 6 7 [/SUP], M H Rahman[SUP] 6 [/SUP], A S M Uddin[SUP] 6 [/SUP], M S Sarker[SUP] 6 [/SUP], T Das[SUP] 8 9 [/SUP], M Hossain[SUP] 10 11 [/SUP], M Khan[SUP] 12 [/SUP], M H Razu[SUP] 12 [/SUP], A Akram[SUP] 13 [/SUP], S Arina[SUP] 13 [/SUP], E Hoque[SUP] 13 [/SUP], M M A Molla[SUP] 13 [/SUP], T Nafisaa[SUP] 13 [/SUP], P Angra[SUP] 14 [/SUP], A Rambaut[SUP] 2 [/SUP], S T Pullan[SUP] 15 [/SUP], K L Osman[SUP] 15 [/SUP], M A Hoque[SUP] 8 [/SUP], P Biswas[SUP] 8 [/SUP], M S Flora[SUP] 16 [/SUP], J Raghwani[SUP] 17 [/SUP], G Fournié[SUP] 17 18 19 [/SUP], M A Samad[SUP] #[/SUP][SUP] 20 [/SUP], S C Hill[SUP] #[/SUP][SUP] 21 [/SUP]
Affiliations
Background: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).
Methods: To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.
Results: We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.
Conclusions: Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.
Keywords: Bangladesh; Genomic epidemiology; Phylodynamics; SARS-CoV-2.
. 2024 Nov 13;21(1):291.
doi: 10.1186/s12985-024-02560-2. Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh
L Carnegie[SUP] #[/SUP][SUP] 1 [/SUP], J T McCrone[SUP] 2 3 [/SUP], L du Plessis[SUP] 4 5 [/SUP], M Hasan[SUP] 6 [/SUP], M Z Ali[SUP] 6 [/SUP], R Begum[SUP] 6 [/SUP], M Z Hassan[SUP] 6 [/SUP], S Islam[SUP] 6 7 [/SUP], M H Rahman[SUP] 6 [/SUP], A S M Uddin[SUP] 6 [/SUP], M S Sarker[SUP] 6 [/SUP], T Das[SUP] 8 9 [/SUP], M Hossain[SUP] 10 11 [/SUP], M Khan[SUP] 12 [/SUP], M H Razu[SUP] 12 [/SUP], A Akram[SUP] 13 [/SUP], S Arina[SUP] 13 [/SUP], E Hoque[SUP] 13 [/SUP], M M A Molla[SUP] 13 [/SUP], T Nafisaa[SUP] 13 [/SUP], P Angra[SUP] 14 [/SUP], A Rambaut[SUP] 2 [/SUP], S T Pullan[SUP] 15 [/SUP], K L Osman[SUP] 15 [/SUP], M A Hoque[SUP] 8 [/SUP], P Biswas[SUP] 8 [/SUP], M S Flora[SUP] 16 [/SUP], J Raghwani[SUP] 17 [/SUP], G Fournié[SUP] 17 18 19 [/SUP], M A Samad[SUP] #[/SUP][SUP] 20 [/SUP], S C Hill[SUP] #[/SUP][SUP] 21 [/SUP]
Affiliations
- PMID: 39538264
- DOI: 10.1186/s12985-024-02560-2
Background: Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world's least developed countries (LDCs).
Methods: To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country's first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.
Results: We detected > 50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.
Conclusions: Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.
Keywords: Bangladesh; Genomic epidemiology; Phylodynamics; SARS-CoV-2.