tetano
Editor, Senior Moderator
Vaccine. 2015 Mar 30. pii: S0264-410X(15)00360-6. doi: 10.1016/j.vaccine.2015.03.052. [Epub ahead of print]
[h=1]Vaccines against influenza A viruses in poultry and swine: Status and future developments.[/h] Rahn J[SUP]1[/SUP], Hoffmann D[SUP]1[/SUP], Harder TC[SUP]1[/SUP], Beer M[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza A viruses are important pathogens with a very broad host spectrum including domestic poultry and swine. For preventing clinical disease and controlling the spread, vaccination is one of the most efficient tools. Classical influenza vaccines for domestic poultry and swine are conventional inactivated preparations. However, a very broad range of novel vaccine types ranging from (i) nucleic acid-based vaccines, (ii) replicon particles, (iii) subunits and virus-like particles, (iv) vectored vaccines, or (v) live-attenuated vaccines has been described, and some of them are now also used in the field. The different novel approaches for vaccines against avian and swine influenza virus infections are reviewed, and additional features like universal vaccines, novel application approaches and the "differentiating infected from vaccinated animals" (DIVA)-strategy are summarized.
Copyright ? 2015 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Chicken; Influenza virus vaccines; Novel developments; Swine
PMID: 25835575 [PubMed - as supplied by publisher]
[h=1]Vaccines against influenza A viruses in poultry and swine: Status and future developments.[/h] Rahn J[SUP]1[/SUP], Hoffmann D[SUP]1[/SUP], Harder TC[SUP]1[/SUP], Beer M[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza A viruses are important pathogens with a very broad host spectrum including domestic poultry and swine. For preventing clinical disease and controlling the spread, vaccination is one of the most efficient tools. Classical influenza vaccines for domestic poultry and swine are conventional inactivated preparations. However, a very broad range of novel vaccine types ranging from (i) nucleic acid-based vaccines, (ii) replicon particles, (iii) subunits and virus-like particles, (iv) vectored vaccines, or (v) live-attenuated vaccines has been described, and some of them are now also used in the field. The different novel approaches for vaccines against avian and swine influenza virus infections are reviewed, and additional features like universal vaccines, novel application approaches and the "differentiating infected from vaccinated animals" (DIVA)-strategy are summarized.
Copyright ? 2015 Elsevier Ltd. All rights reserved.
[h=4]KEYWORDS:[/h] Chicken; Influenza virus vaccines; Novel developments; Swine
PMID: 25835575 [PubMed - as supplied by publisher]