tetano
Editor, Senior Moderator
Vaccine
. 2025 Jul 8:62:127442.
doi: 10.1016/j.vaccine.2025.127442. Online ahead of print. School-based interventions to increase influenza vaccination in primary school students
Mengmeng Jia[SUP] 1 [/SUP], Yanlin Cao[SUP] 2 [/SUP], Xin Mu[SUP] 3 [/SUP], Dafei Ren[SUP] 4 [/SUP], Jiuquan Ai[SUP] 5 [/SUP], Cai Yang[SUP] 3 [/SUP], Ping Zhang[SUP] 4 [/SUP], Yuxi Liu[SUP] 2 [/SUP], Yuandong Hu[SUP] 6 [/SUP], Luzhao Feng[SUP] 7 [/SUP]
Affiliations
Background: Addressing low vaccination coverage in primary school students will help prevent influenza outbreaks and safeguard public health. We evaluated the effectiveness of school-based interventions in improving influenza vaccination rates among primary school students in Guizhou, China.
Methods: Parents and students from four primary schools participated in December 2023. Basic information and vaccination history were collected at baseline and on April 30, 2024, respectively. Among the 9437 included students, 9168 (97·15 %) were not vaccinated during the 2023-2024 winter season. In one school, parents received informational material (Information group); in another, children received on-campus influenza vaccination services (SIV group). A third school received both informational material and vaccination services (Information+SIV group). The fourth was the control group, receiving no intervention.
Findings: Since the intervention, 1·11 % (19/1713) of previously unvaccinated students in the 2023-2024 season were vaccinated in the control group. Vaccination rates were significantly higher in the Information (5·30 %, P < 0·001), SIV (13·99 %, P < 0·001), and Information+SIV groups (12·96 %, P < 0·001) than in the control group. The SIV and Information+SIV groups had higher vaccination rates than the Information group (P < 0·01), with no significant difference between the SIV and Information+SIV groups (P = 0·28). Among the 853 vaccinated students, 44·78 % (n = 382) were first-time recipients. Those with prior vaccination history had a higher likelihood of vaccination than their counterparts. Students in grades 5-6 and some ethnic minority groups had a lower likelihood of vaccination.
Interpretation: School-based interventions, particularly on-campus vaccinations, can increase vaccination rates among primary school students.
Funding: Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (grant number: 2022-12 M-CoV19-004), Science & Technology Fundamental Resources Investigation Program (grant number: 2023FY100600), Gates Foundation (grant number: INV-023808, INV-006373), and Health Commission of Guizhou Province (grant number: gzwkj2024-215).
Keywords: Influenza vaccines; Intervention; Primary school; Vaccine coverage.
. 2025 Jul 8:62:127442.
doi: 10.1016/j.vaccine.2025.127442. Online ahead of print. School-based interventions to increase influenza vaccination in primary school students
Mengmeng Jia[SUP] 1 [/SUP], Yanlin Cao[SUP] 2 [/SUP], Xin Mu[SUP] 3 [/SUP], Dafei Ren[SUP] 4 [/SUP], Jiuquan Ai[SUP] 5 [/SUP], Cai Yang[SUP] 3 [/SUP], Ping Zhang[SUP] 4 [/SUP], Yuxi Liu[SUP] 2 [/SUP], Yuandong Hu[SUP] 6 [/SUP], Luzhao Feng[SUP] 7 [/SUP]
Affiliations
- PMID: 40633128
- DOI: 10.1016/j.vaccine.2025.127442
Background: Addressing low vaccination coverage in primary school students will help prevent influenza outbreaks and safeguard public health. We evaluated the effectiveness of school-based interventions in improving influenza vaccination rates among primary school students in Guizhou, China.
Methods: Parents and students from four primary schools participated in December 2023. Basic information and vaccination history were collected at baseline and on April 30, 2024, respectively. Among the 9437 included students, 9168 (97·15 %) were not vaccinated during the 2023-2024 winter season. In one school, parents received informational material (Information group); in another, children received on-campus influenza vaccination services (SIV group). A third school received both informational material and vaccination services (Information+SIV group). The fourth was the control group, receiving no intervention.
Findings: Since the intervention, 1·11 % (19/1713) of previously unvaccinated students in the 2023-2024 season were vaccinated in the control group. Vaccination rates were significantly higher in the Information (5·30 %, P < 0·001), SIV (13·99 %, P < 0·001), and Information+SIV groups (12·96 %, P < 0·001) than in the control group. The SIV and Information+SIV groups had higher vaccination rates than the Information group (P < 0·01), with no significant difference between the SIV and Information+SIV groups (P = 0·28). Among the 853 vaccinated students, 44·78 % (n = 382) were first-time recipients. Those with prior vaccination history had a higher likelihood of vaccination than their counterparts. Students in grades 5-6 and some ethnic minority groups had a lower likelihood of vaccination.
Interpretation: School-based interventions, particularly on-campus vaccinations, can increase vaccination rates among primary school students.
Funding: Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (grant number: 2022-12 M-CoV19-004), Science & Technology Fundamental Resources Investigation Program (grant number: 2023FY100600), Gates Foundation (grant number: INV-023808, INV-006373), and Health Commission of Guizhou Province (grant number: gzwkj2024-215).
Keywords: Influenza vaccines; Intervention; Primary school; Vaccine coverage.