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Vaccine . Influenza vaccine acceptance and hesitancy among adults hospitalized with severe acute respiratory illnesses, United States 2019-2020

tetano

Editor, Senior Moderator
Vaccine


. 2021 Aug 7;S0264-410X(21)00948-8.
doi: 10.1016/j.vaccine.2021.07.057. Online ahead of print.
Influenza vaccine acceptance and hesitancy among adults hospitalized with severe acute respiratory illnesses, United States 2019-2020


Kelsey L Lytle[SUP] 1 [/SUP], Sean P Collins[SUP] 1 [/SUP], Leora R Feldstein[SUP] 2 [/SUP], Adrienne H Baughman[SUP] 1 [/SUP], Samuel M Brown[SUP] 3 [/SUP], Jonathan D Casey[SUP] 1 [/SUP], Heidi L Erickson[SUP] 4 [/SUP], Matthew C Exline[SUP] 5 [/SUP], D Clark Files[SUP] 6 [/SUP], Kevin W Gibbs[SUP] 6 [/SUP], Adit A Ginde[SUP] 7 [/SUP], Michelle N Gong[SUP] 8 [/SUP], Carlos G Grijalva[SUP] 1 [/SUP], Akram Khan[SUP] 9 [/SUP], Christopher J Lindsell[SUP] 1 [/SUP], Ithan D Peltan[SUP] 3 [/SUP], Matthew E Prekker[SUP] 4 [/SUP], Todd W Rice[SUP] 1 [/SUP], Nathan I Shapiro[SUP] 10 [/SUP], Jay S Steingrub[SUP] 11 [/SUP], William B Stubblefield[SUP] 1 [/SUP], Mark W Tenforde[SUP] 2 [/SUP], Kelsey N Womack[SUP] 1 [/SUP], Manish M Patel[SUP] 2 [/SUP], Wesley H Self[SUP] 12 [/SUP], Influenza and Other Viruses in the Acutely Ill (IVY) Network



Affiliations

Abstract

Introduction: Understanding patient factors associated with not being vaccinated is essential for successful implementation of influenza vaccination programs.
Methods: We enrolled adults hospitalized with severe acute respiratory illness at 10 United States (US) hospitals during the 2019-2020 influenza season. We interviewed patients to collect data about influenza vaccination, sociodemographic characteristics, and vaccine perceptions.
Results: Among 679 participants, 264 (38.9%) reported not receiving influenza vaccination. Among those not vaccinated, 135 (51.1%) reported choosing not to receive a vaccine because of perceived ineffectiveness (36.7%) or risk (14.4%) of influenza vaccination. Sociodemographic factors associated with not being vaccinated included no medical insurance (aOR = 6.42; 95% CI: 2.52-16.38) and being non-White or Hispanic (aOR = 1.54, 95% CI: 1.02-2.32).
Conclusions: Optimizing uptake of influenza vaccination in the US may be improved by educational programs regarding vaccine safety and effectiveness and enhancing vaccine access, particularly among non-White and Hispanic Americans and those without medical insurance.

Keywords: Influenza; Medical insurance; Vaccination; Vaccine acceptance; Vaccine hesitancy.
 
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