Vaccine . Influenza vaccination effectiveness in preventing influenza hospitalization in children, Hong Kong, winter 2019/20

[tetano]

Vaccine


. 2020 Nov 6;S0264-410X(20)31401-8.
doi: 10.1016/j.vaccine.2020.10.081. Online ahead of print.
Influenza vaccination effectiveness in preventing influenza hospitalization in children, Hong Kong, winter 2019/20


Susan S Chiu[SUP] 1 [/SUP], Huiying Chua[SUP] 2 [/SUP], Mike Y W Kwan[SUP] 3 [/SUP], Eunice L Y Chan[SUP] 1 [/SUP], Joshua S C Wong[SUP] 3 [/SUP], J S Malik Peiris[SUP] 2 [/SUP], Benjamin J Cowling[SUP] 4 [/SUP]



Affiliations

• PMID: 33168346
• DOI: 10.1016/j.vaccine.2020.10.081

Abstract

The winter influenza season 2019/20 in Hong Kong was predominated by influenza A(H1N1)pdm09. We analysed an on-going test-negative design study consisting of 1227 children admitted for febrile acute respiratory illness from 3 November 2019 (week 45) to 21 March 2020 (week 12). We estimated influenza vaccine effectiveness of 65% (95% CI: 46 - 78) against hospitalization due to influenza A and B combined, and 74% (95% CI: 54 - 85) against hospitalization due to influenza A(H1N1)pdm09.

Keywords: Children; Hospitalization; Influenza; Vaccine effectiveness.