tetano
Editor, Senior Moderator
Vaccine
. 2025 Feb 16:51:126864.
doi: 10.1016/j.vaccine.2025.126864. Online ahead of print. Dementia and influenza vaccination: Time trends and predictors of vaccine uptake among older adults
Andreas Moses Appel[SUP] 1 [/SUP], Janet Janbek[SUP] 2 [/SUP], Thomas Munk Laursen[SUP] 3 [/SUP], Christiane Gasse[SUP] 4 [/SUP], Gunhild Waldemar[SUP] 5 [/SUP], Christina Jensen-Dahm[SUP] 2 [/SUP]
Affiliations
Purpose: Older adults with dementia are at an increased risk of hospitalizations with respiratory infections and death, emphasizing the need for a greater focus on preventive measures. In this study, we investigated the uptake of influenza vaccines among older adults with and without dementia.
Methods: We conducted a cross-sectional study with data from national registries on the entire Danish population aged ≥65 years. We mapped time trends of vaccination for each vaccination season (September to August) from 2002/03 to 2018/19. Using multivariable logistic regression, we estimated the odds of vaccination in 2018/19 in nursing home residents and home-living older adults with and without dementia.
Results: We included 800,387 individuals in 2002/03 and 1,122,319 in 2018/19. After a period of similar and increasing uptake of influenza vaccines among people with and without dementia, the uptake plateaued from 2007/08 to 2018/19 and was consistently higher in those with dementia during this period. The odds of vaccination in 2018/19 were lower for home-living people with dementia compared to home-living people without dementia (OR: 0.76; 95 % CI: 0.74-0.78). The highest odds were among nursing home residents both with (OR: 1.28; 95 % CI:1.24-1.33) and without dementia (1.18; 95 % CI: 1.14-1.22).
Conclusion: Between 2002/03 and 2018/19 vaccine coverage among older adults in Denmark was <60 %, regardless of dementia status, not reaching the WHO target of 75 %. Home-living older adults with dementia were 24 % less likely to receive an influenza vaccine, representing an important target group for future vaccination programs.
Keywords: Aging; Dementia; Influenza; Prevention; Vaccination.
. 2025 Feb 16:51:126864.
doi: 10.1016/j.vaccine.2025.126864. Online ahead of print. Dementia and influenza vaccination: Time trends and predictors of vaccine uptake among older adults
Andreas Moses Appel[SUP] 1 [/SUP], Janet Janbek[SUP] 2 [/SUP], Thomas Munk Laursen[SUP] 3 [/SUP], Christiane Gasse[SUP] 4 [/SUP], Gunhild Waldemar[SUP] 5 [/SUP], Christina Jensen-Dahm[SUP] 2 [/SUP]
Affiliations
- PMID: 39961204
- DOI: 10.1016/j.vaccine.2025.126864
Purpose: Older adults with dementia are at an increased risk of hospitalizations with respiratory infections and death, emphasizing the need for a greater focus on preventive measures. In this study, we investigated the uptake of influenza vaccines among older adults with and without dementia.
Methods: We conducted a cross-sectional study with data from national registries on the entire Danish population aged ≥65 years. We mapped time trends of vaccination for each vaccination season (September to August) from 2002/03 to 2018/19. Using multivariable logistic regression, we estimated the odds of vaccination in 2018/19 in nursing home residents and home-living older adults with and without dementia.
Results: We included 800,387 individuals in 2002/03 and 1,122,319 in 2018/19. After a period of similar and increasing uptake of influenza vaccines among people with and without dementia, the uptake plateaued from 2007/08 to 2018/19 and was consistently higher in those with dementia during this period. The odds of vaccination in 2018/19 were lower for home-living people with dementia compared to home-living people without dementia (OR: 0.76; 95 % CI: 0.74-0.78). The highest odds were among nursing home residents both with (OR: 1.28; 95 % CI:1.24-1.33) and without dementia (1.18; 95 % CI: 1.14-1.22).
Conclusion: Between 2002/03 and 2018/19 vaccine coverage among older adults in Denmark was <60 %, regardless of dementia status, not reaching the WHO target of 75 %. Home-living older adults with dementia were 24 % less likely to receive an influenza vaccine, representing an important target group for future vaccination programs.
Keywords: Aging; Dementia; Influenza; Prevention; Vaccination.