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Vaccine. Brainstem encephalitis following influenza vaccination: Favorable response to steroid treatment.

Giuseppe

Emeritus
Vaccine. 2009 Sep 10. [Epub ahead of print]

Brainstem encephalitis following influenza vaccination: Favorable response to steroid treatment.

T?rkoğlu R, T?z?n E. - Department of Neurology, Haydarpasa Numune State Hospital, Istanbul, Turkey.

We report a 44-year-old man presenting with left hemiparesis following influenza vaccination. The neuroimaging studies showed a large, contrast-enhancing brainstem lesion and multiple punctate lesions suggesting microhaemorrhages in both cerebral hemispheres. The patient showed a remarkable response to high dose steroid treatment. Detailed diagnostic studies failed to yield any results supporting inflammatory/demyelinating diseases, suggesting that influenza vaccination might have been associated with the clinical findings. Our case implies that vaccination might be related with a wide range of clinical syndromes, including brainstem encephalitis.

PMID: 19748576 [PubMed - as supplied by publisher]

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