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US Congressional Research Service - H5N1 Avian Influenza: The Human Health Response

Commonground

Senior Moderator
February 4, 2025


Since early 2022, a U.S. H5N1 avian influenza (“bird flu”)

outbreak in poultry and wild birds has led to outbreaks in

dairy herds. Increasing cases of transmission from animals

to humans occurred in 2024. H5N1 influenza is a subtype

of influenza A virus that causes highly pathogenic avian

influenza, a form of influenza that is highly contagious and

deadly to birds. The virus has adapted to spread among

certain mammal species such as cattle and cats. Currently,

H5N1 influenza is not known to spread easily from human

to human. To date, most human H5N1 influenza cases have

been associated with animal exposures, with very few cases

due to human-to-human transmission. Yet many

uncertainties persist around if and when H5N1 influenza

virus might adapt to spread more easily among humans,

potentially resulting in a pandemic. In this case, most

people would not have prior immunity to H5N1 influenza

virus, which means the virus could spread quickly. The

virus’s growing spread among animals creates more

opportunities for a strain with human pandemic potential to

emerge.

continued: https://crsreports.congress.gov/product/pdf/IF/IF12895
 
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