Unravelling the complexity of a pandemic shaped by mass vaccination. What does it tell us?

[Emily]

https://www.geertvandenbossche.org/...aped-by-mass-vaccination-what-does-it-tell-us

• • 2 days ago
  • 5 min read

Unravelling the complexity of a pandemic shaped by mass vaccination. What does it tell us?

Geert Vanden Bossche (DVM, PhD)

.....

Conclusion:

Whether ?home-made? or ?foreign?, vaccine-resistant variants are highly likely to cause more (severe) disease in vaccinated as compared to non-vaccinated subjects. This is because the latter may still dispose upon a fully functional arsenal of CoV-nonspecific Abs provided they are seronegative for CoV-derived S protein. As a result, vaccinees will soon constitute the predominant source of Sars-CoV-2 infection and cause a dramatic surge in viral infectious pressure. As pre-symptomatic vaccinees will increasingly serve as a reservoir for Sars-CoV-2 infection, non-vaccinated persons should refrain from mixing with vaccinees.

As patients with severe Covid-19 disease need hospitalization, circulation of vaccine-resistant variants is not only going to overwhelm the health care system but also pose a tremendous risk to all health care workers as the vast majority of them have already been vaccinated. Consequently, health care workers as well will be much more susceptible to contracting Covid-19 disease caused by vaccine-resistant variants....

 

[JJackson]

Based on his credentials the author needs to be taken seriously but I have my doubts. Vaccine escape variants are as likely to be milder and less transmissible than the reverse there rise against the wild types is due to the vaccinated / previously infected not handling them quite as well as the version they had already encountered. This is not an all or nothing distinction as most of the epitopes are the same, only a handful of changes among thousands, giving the novel variants a slight fitness advantage, likewise the vaccine will still work well just not quite as well.

 

[GardenSpider]

His scientific hypothesis is very interesting and worth understanding. Whether it is correct or not, time will tell. But given the open questions regarding how immunity actually works, it may be worthwhile to those curious to hear him explain it clearly in this podcast. Sometimes the outliers are on to something everyone else has missed.

https://www.youtube.com/watch?v=2LSMpuQcTSE

 

[bertrand789]

la première des erreurs est d'avoir mal nommée cette situation. Nous sommes face à une syndémie et nous laissons des petites têtes user d'outils pas fait pour cela ...


la même "youtube" en langue de Molière ce serait sympa pour les autres ...

 

[Pathfinder]

Mass Vaccination in the Middle of Pandemic Underestimates Evolutionary Capacity of SARS-CoV2 to Evolve

PaulAlexander
December 5, 2021

Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite

Paul Elias Alexander, MHSc, MSc, PhD, Geert Vanden Bossche, DVM, PhD

Mass population vaccination and the resultant immune pressure amidst high infectious pressure underestimates the evolutionary capacity of SARS-CoV-2 to evolve: this is as unwise and misguided as disregarding fully vaccinated persons as a major source of COVID virus transmission.

We function here as prognosticators, skeptics, and contrarians with the aim only of sharing our opinion and information for the reader for more informed reflection and decision making. We are also writing to global governments, their Task Forces, and vaccine decision makers in this particular piece.

There has been a tremendous underestimation of the evolutionary capacity of SARS-CoV-2 virus when it is put under widespread immune pressure. We refer here to the immune pressure from the vaccine (e.g. vaccinal antibodies). In our estimation, there can be no doubt that the recently reported Omicron variant is only one such example of this evolution and that other variants harboring a similar panoply of S (spike)-directed mutations will soon emerge in other countries. There is, indeed, no reason to accept or believe that identical conditions of suboptimal population-level immune pressure (due to the vaccine) on SARS-CoV-2 infectiousness combined with widespread infectious pressure (due to vaccination in the midst of a viral epidemic/pandemic) would result in a different outcome. Countries which have implemented mass vaccination programs have created the conditions as excellent breeding grounds for more infectious variants. These countries will exhibit a high level of hospitality to Omicron and its peers.

The good news is emerging evidence that the Omicron variant is very mild, even milder than the mild Delta variant, with much lower transmissibility. This is based on modeling analysis of potential transmissibility, “based on the S1 receptor binding domain mutations”. Cases may even decline due to this. We see no data to indicate otherwise, recognizing we are early in the reporting. We expect this to remain so however (while cautious). Moreover, epidemiologist and cardiologist Dr. Peter McCullough has indicated from his analysis that Omicron variant may carve out its own ecological niche much alike epsilon and lamda, with no usurping of the predominant global position held by Delta variant.

...
https://trialsitenews.com/mass-vacc...evolutionary-capacity-of-sars-cov2-to-evolve/

 

[Emily]

Omicron with all its unexpected mutations is what I would call a 'Black Swan' event. Once again we have an evolutionary mystery. Black Swans are usually associated with catastrophes in the realm of economics. Biology and social reactions to that realm are far more complex, so I hope the opposite will be true in this case.

 

[Pathfinder]

Hattip Emily :

October 11, 2022

It is 5 past 12 !
...
Hello everyone. My name is Geert Vanden Bossche. I'm a seasoned vaccinologist with background in veterinary medicine, in biology, immunology, microbial diseases.
...
Please remember only herd immunity can terminate the pandemic. So, you have the choice. You can either reduce this transmission by enhancing the virulence in the vaccinees, what the virus tends to do. If the virulence of the virus increases in the vaccinees, yeah, then of course you are going to have plenty of vaccinees who do no longer transmit. Even if they don't die, they will at least develop severe disease and, therefore, be hospitalized; they will be out of society and this will dramatically diminish the transmission rate. Do we want to let this happen given the high risk of death, of mortality, or severe morbidity? The only alternative is to provide these people with antivirals, antiviral chemoprophylaxis.

These are the only two options that we have to diminish this fulminant transmission rate in the population that we see right now and that could lead to this miraculous target that was in fact the purpose of the mass vaccination campaign, which miserably failed, and which is herd immunity.

So, what about the side effects and all post mortality rates in the vaccinees that we have seen have been going up? It's appalling if you see the rates and the kind of side effects, the kind of increase in excess deaths, etc. I have no words to describe it; really. It's appalling, it is unacceptable, it blows me away.

But nevertheless, whether you believe me or not, I'm always saying: if one puts all these side effects and all this excess death rate together, it is still going to be peanuts compared to the kind of losses that we are going to face when the virus evolves as I'm predicting, and which I'm 200% certain of, that it will evolve in that way.

And what about early treatment? Well, that is why I'm recommending to do chemoprophylaxis even before people get infected, because there is a high risk that early treatment will be ‘too little’ and that it will come ‘too late’. Why? Because I was just telling you that the virus is now evolving not only to become completely resistant to neutralizing antibodies, but also to become more infectious.
...
https://www.voiceforscienceandsolidarity.org/videos-and-interviews/it-is-5-past-12


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October 13, 2022

Dr. Vanden Bossche and Dr. Alexander: Pfizer's failure to test COVID vaccines for transmission

Dr. Geert Vanden Bossche and Dr. Paul Elias Alexander discuss Pfizer's failure to test COVID vaccines for transmission, the need for population chemoprophylaxis, and recommendations for the unvaccinated and vaccinated. October 13, 2022
...

Video:
https://www.voiceforscienceandsolid...ilure-to-test-covid-vaccines-for-transmission