tetano
Editor, Senior Moderator
Am J Public Health. 2013 Dec 12. [Epub ahead of print]
Unraveling R0: Considerations for Public Health Applications.
Ridenhour B, Kowalik JM, Shay DK.
Author information
Abstract
We assessed public health use of R0, the basic reproduction number, which estimates the speed at which a disease is capable of spreading in a population. These estimates are of great public health interest, as evidenced during the 2009 influenza A (H1N1) virus pandemic. We reviewed methods commonly used to estimate R0, examined their practical utility, and assessed how estimates of this epidemiological parameter can inform mitigation strategy decisions. In isolation, R0 is a suboptimal gauge of infectious disease dynamics across populations; other disease parameters may provide more useful information. Nonetheless, estimation of R0 for a particular population is useful for understanding transmission in the study population. Considered in the context of other epidemiologically important parameters, the value of R0 may lie in better understanding an outbreak and in preparing a public health response. (Am J Public Health. Published online ahead of print December 12, 2013: e1-e10. doi:10.2105/AJPH.2013.301704).
PMID:
24328646
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24328646
Unraveling R0: Considerations for Public Health Applications.
Ridenhour B, Kowalik JM, Shay DK.
Author information
Abstract
We assessed public health use of R0, the basic reproduction number, which estimates the speed at which a disease is capable of spreading in a population. These estimates are of great public health interest, as evidenced during the 2009 influenza A (H1N1) virus pandemic. We reviewed methods commonly used to estimate R0, examined their practical utility, and assessed how estimates of this epidemiological parameter can inform mitigation strategy decisions. In isolation, R0 is a suboptimal gauge of infectious disease dynamics across populations; other disease parameters may provide more useful information. Nonetheless, estimation of R0 for a particular population is useful for understanding transmission in the study population. Considered in the context of other epidemiologically important parameters, the value of R0 may lie in better understanding an outbreak and in preparing a public health response. (Am J Public Health. Published online ahead of print December 12, 2013: e1-e10. doi:10.2105/AJPH.2013.301704).
PMID:
24328646
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24328646