tetano
Editor, Senior Moderator
Transplant Proc
. 2022 Jun 1;S0041-1345(22)00390-6.
doi: 10.1016/j.transproceed.2022.05.010. Online ahead of print.
Mortality Due to COVID-19 in Renal Transplant Recipients, Related to Variants of SARS-CoV-2 and Vaccination in Mexico
Juan Carlos H Hernández Rivera[SUP] 1 [/SUP], Mariana Salazar Mendoza[SUP] 2 [/SUP], Luis García Covarrubias[SUP] 3 [/SUP], Ana Laura Quiroz Ramírez[SUP] 4 [/SUP], Lizbeth Chicas Reyes[SUP] 4 [/SUP], Manuel Bautista Hernández[SUP] 4 [/SUP], Jorge Romero Martínez[SUP] 4 [/SUP], Yohaheri Pineda Contla[SUP] 4 [/SUP], Julissa Madai Velasco Durán[SUP] 4 [/SUP], Agustín Trejo Rivas[SUP] 4 [/SUP], Samantha Lorelae Rodríguez Flores[SUP] 4 [/SUP], Walter Adolfo Querevalú Murillo[SUP] 5 [/SUP], José Ramón Paniagua Sierra[SUP] 6 [/SUP]
Affiliations
Abstract
Background: SARS-CoV-2 infection in transplant patients has shown greater lethality and vaccination in this group of patients has shown less information. The objective of this study is to show the statistics in Mexico of lethality in kidney recipients infected with COVID-19 in relation to vaccination and variants of the coronavirus.
Methods: This is a bibliographic search of kidney transplant recipient patients since the start of the pandemic in Mexico to determine lethality after SARS-CoV-2 compared to the general population and in relation to patients, the 4 most important infectious peaks in the country due to identified variants, and also before and after vaccination.
Results: The global lethality is 26.91% from the beginning of the pandemic to April 9, 2022 in kidney recipients in Mexico (130 deaths of 483 infected kidney transplant recipients) compared to the national lethality of 5.60%. Variant B. 1.1.220 represented the highest lethality with 30.43% and the lowest lethality was Omicron with 16.41%. The lethality prior to vaccination was 30.94% and 23.46% after it.
Conclusion: Both some variants and vaccination have influenced a lower lethality due to COVID-19 in Mexico in kidney transplant patients; It is important to consider global recommendations, such as a third or fourth dose, a combination of mRNA vaccines and vectors in order to reduce lethality in this group of patients.
. 2022 Jun 1;S0041-1345(22)00390-6.
doi: 10.1016/j.transproceed.2022.05.010. Online ahead of print.
Mortality Due to COVID-19 in Renal Transplant Recipients, Related to Variants of SARS-CoV-2 and Vaccination in Mexico
Juan Carlos H Hernández Rivera[SUP] 1 [/SUP], Mariana Salazar Mendoza[SUP] 2 [/SUP], Luis García Covarrubias[SUP] 3 [/SUP], Ana Laura Quiroz Ramírez[SUP] 4 [/SUP], Lizbeth Chicas Reyes[SUP] 4 [/SUP], Manuel Bautista Hernández[SUP] 4 [/SUP], Jorge Romero Martínez[SUP] 4 [/SUP], Yohaheri Pineda Contla[SUP] 4 [/SUP], Julissa Madai Velasco Durán[SUP] 4 [/SUP], Agustín Trejo Rivas[SUP] 4 [/SUP], Samantha Lorelae Rodríguez Flores[SUP] 4 [/SUP], Walter Adolfo Querevalú Murillo[SUP] 5 [/SUP], José Ramón Paniagua Sierra[SUP] 6 [/SUP]
Affiliations
- PMID: 35931470
- PMCID: PMC9156950
- DOI: 10.1016/j.transproceed.2022.05.010
Abstract
Background: SARS-CoV-2 infection in transplant patients has shown greater lethality and vaccination in this group of patients has shown less information. The objective of this study is to show the statistics in Mexico of lethality in kidney recipients infected with COVID-19 in relation to vaccination and variants of the coronavirus.
Methods: This is a bibliographic search of kidney transplant recipient patients since the start of the pandemic in Mexico to determine lethality after SARS-CoV-2 compared to the general population and in relation to patients, the 4 most important infectious peaks in the country due to identified variants, and also before and after vaccination.
Results: The global lethality is 26.91% from the beginning of the pandemic to April 9, 2022 in kidney recipients in Mexico (130 deaths of 483 infected kidney transplant recipients) compared to the national lethality of 5.60%. Variant B. 1.1.220 represented the highest lethality with 30.43% and the lowest lethality was Omicron with 16.41%. The lethality prior to vaccination was 30.94% and 23.46% after it.
Conclusion: Both some variants and vaccination have influenced a lower lethality due to COVID-19 in Mexico in kidney transplant patients; It is important to consider global recommendations, such as a third or fourth dose, a combination of mRNA vaccines and vectors in order to reduce lethality in this group of patients.