tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2015 May 23. doi: 10.1111/irv.12329. [Epub ahead of print]
[h=1]Transmission Dynamics of Pandemic Influenza A(H1N1)pdm09 Virus in Humans and Swine in Backyard Farms in Tumbes, Peru.[/h] Tinoco YO[SUP]1,[/SUP][SUP]2[/SUP], Montgomery JM[SUP]1,[/SUP][SUP]3[/SUP], Kasper MR[SUP]1[/SUP], Nelson MI[SUP]4[/SUP], Azziz-Baumgartner E[SUP]5[/SUP], Gilman RH[SUP]2[/SUP], Bausch DG[SUP]1,[/SUP][SUP]6[/SUP], Gonzalez AE[SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Although influenza A(H1N1)pdm09 virus (pH1N1) is known to infect swine, the transmission of pH1N1 between humans and swine have not been explored among the smaller scale backyard farm settings that predominate in many developing countries, and where there may be important opportunities for influenza virus transmission between humans and livestock.
[h=4]OBJECTIVES:[/h] We aimed to determine the frequency of pH1N1 transmission between humans and swine on backyard farms in Tumbes, Peru.
[h=4]METHODS:[/h] We conducted a two-year serial cross-sectional study, assessing current and past pH1N1 infection in swine through serological testing, virus culture and RT-PCR, and compared the results with human incidence data from a population-based active surveillance cohort study in Peru.
[h=4]RESULTS:[/h] mong 1,303 swine sampled, the antibody prevalence to pH1N1 was 0% pre-pandemic, 8% at the peak of the human pandemic (October 2009), and 24% in April 2010 and 1% in October 2011 (post-pandemic sampling periods). Trends in swine seropositivity paralleled those seen in humans in Tumbes. The pH1N1 virus was isolated from 3 pigs during the peak of the pandemic. Phylogenetic analysis revealed that these viruses likely represent two separate human-to-swine transmission events in backyard farm settings.
[h=4]CONCLUSIONS:[/h] Our findings suggest that human-to-swine pH1N1 transmission occurred during the pandemic among backyard farms in Peru, emphasizing the importance of inter-species transmission in backyard pig populations. Continued surveillance for influenza viruses in backyard farms is warranted. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Antibodies; backyard pig farms; human-animal transmission; influenza
PMID: 26011186 [PubMed - as supplied by publisher]
[h=1]Transmission Dynamics of Pandemic Influenza A(H1N1)pdm09 Virus in Humans and Swine in Backyard Farms in Tumbes, Peru.[/h] Tinoco YO[SUP]1,[/SUP][SUP]2[/SUP], Montgomery JM[SUP]1,[/SUP][SUP]3[/SUP], Kasper MR[SUP]1[/SUP], Nelson MI[SUP]4[/SUP], Azziz-Baumgartner E[SUP]5[/SUP], Gilman RH[SUP]2[/SUP], Bausch DG[SUP]1,[/SUP][SUP]6[/SUP], Gonzalez AE[SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Although influenza A(H1N1)pdm09 virus (pH1N1) is known to infect swine, the transmission of pH1N1 between humans and swine have not been explored among the smaller scale backyard farm settings that predominate in many developing countries, and where there may be important opportunities for influenza virus transmission between humans and livestock.
[h=4]OBJECTIVES:[/h] We aimed to determine the frequency of pH1N1 transmission between humans and swine on backyard farms in Tumbes, Peru.
[h=4]METHODS:[/h] We conducted a two-year serial cross-sectional study, assessing current and past pH1N1 infection in swine through serological testing, virus culture and RT-PCR, and compared the results with human incidence data from a population-based active surveillance cohort study in Peru.
[h=4]RESULTS:[/h] mong 1,303 swine sampled, the antibody prevalence to pH1N1 was 0% pre-pandemic, 8% at the peak of the human pandemic (October 2009), and 24% in April 2010 and 1% in October 2011 (post-pandemic sampling periods). Trends in swine seropositivity paralleled those seen in humans in Tumbes. The pH1N1 virus was isolated from 3 pigs during the peak of the pandemic. Phylogenetic analysis revealed that these viruses likely represent two separate human-to-swine transmission events in backyard farm settings.
[h=4]CONCLUSIONS:[/h] Our findings suggest that human-to-swine pH1N1 transmission occurred during the pandemic among backyard farms in Peru, emphasizing the importance of inter-species transmission in backyard pig populations. Continued surveillance for influenza viruses in backyard farms is warranted. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Antibodies; backyard pig farms; human-animal transmission; influenza
PMID: 26011186 [PubMed - as supplied by publisher]