Mary Wilson
Well-known member
29 June 2021
https://doi.org/10.7326/L21-0244
Swathi Sangli, MBBS, Ahmed Virani, MD, Nicholas Cheronis, MD, Brittany Vannatter, DO, Corbyn Minich, DO, Shaun Noronha, MBBS, Rama Bhagavatula, MD, Daniel Speredelozzi, MD, Meera Sareen, MD, Robert B. Kaplan, MD
Background: Thrombosis with thrombocytopenia has been reported after vaccination against SARS-CoV-2 with 2 vaccines based on recombinant adenovirus vectors—the ChAdOx1 vaccine from AstraZeneca (1, 2) and the Ad26.COV2.S vaccine from Johnson & Johnson/Janssen (3). This syndrome is similar to heparin-induced thrombocytopenia (HIT), and it is known as vaccine-induced thrombosis with thrombocytopenia (VITT) or thrombocytopenia with thrombosis syndrome (TTS). To our knowledge, there are no reports of VITT or TTS after a SARS-CoV-2 vaccine based on messenger RNA (mRNA) technology (4).
Objective: To describe a patient with VITT or TTS after administration of the mRNA-1273 vaccine from Moderna.
https://www.acpjournals.org/doi/10.7326/L21-0244
https://doi.org/10.7326/L21-0244
Swathi Sangli, MBBS, Ahmed Virani, MD, Nicholas Cheronis, MD, Brittany Vannatter, DO, Corbyn Minich, DO, Shaun Noronha, MBBS, Rama Bhagavatula, MD, Daniel Speredelozzi, MD, Meera Sareen, MD, Robert B. Kaplan, MD
Background: Thrombosis with thrombocytopenia has been reported after vaccination against SARS-CoV-2 with 2 vaccines based on recombinant adenovirus vectors—the ChAdOx1 vaccine from AstraZeneca (1, 2) and the Ad26.COV2.S vaccine from Johnson & Johnson/Janssen (3). This syndrome is similar to heparin-induced thrombocytopenia (HIT), and it is known as vaccine-induced thrombosis with thrombocytopenia (VITT) or thrombocytopenia with thrombosis syndrome (TTS). To our knowledge, there are no reports of VITT or TTS after a SARS-CoV-2 vaccine based on messenger RNA (mRNA) technology (4).
Objective: To describe a patient with VITT or TTS after administration of the mRNA-1273 vaccine from Moderna.
https://www.acpjournals.org/doi/10.7326/L21-0244