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The Study of Respiratory Pathogens in Andean Children

tetano

Editor, Senior Moderator
Int J Epidemiol. 2013 Jun 14. [Epub ahead of print]
The Study of Respiratory Pathogens in Andean Children.
Grijalva CG, Griffin MR, Edwards KM, Williams JV, Gil AI, Verastegui H, Hartinger SM, Vidal JE, Klugman KP, Lanata CF.
Source

Departments of Preventive Medicine, Vanderbilt University School of Medicine, Nashville TN, USA, Pediatrics-Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville TN, USA, Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville TN, USA, Instituto de Investigaci?n Nutricional, Lima, Per?, Swiss Tropical and Public Health Institute, Basel, Switzerland and Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta GA, USA.
Abstract

We investigated respiratory pathogens in a prospective cohort study of young children living in the Peruvian Andes. In the study we assessed viral respiratory infections among young children, and explored interactions of viruses with common respiratory bacteria, especially Streptococcus pneumoniae. Through weekly household visits, data were collected on the signs and symptoms of acute respiratory illness (ARI), nasal samples were collected to test for viruses during episodes of ARI, and nasopharyngeal samples were collected on a monthly basis to monitor bacterial colonisation. We also collected data on vaccination coverage, patterns of social mixing, geographic information, and environmental and socio-demographic variables. Understanding the interaction of respiratory viruses with bacteria and its impact on the burden and severity of ARIs in rural areas of developing countries is critical to designing strategies for preventing such infections. Investigators interested in more details about this study or in accessing these resources should contact Dr. Carlos G. Grijalva at Vanderbilt University (carlos.grijalva@vanderbilt.edu).
KEYWORDS:

Epidemiology, acute respiratory illness, children, influenza, pneumococcus

PMID:
23771719
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/23771719
 
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