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The presence of fever in adults with influenza and other viral respiratory infections

tetano

Editor, Senior Moderator
Epidemiol Infect. 2016 Oct 3:1-8. [Epub ahead of print]
[h=1]The presence of fever in adults with influenza and other viral respiratory infections.[/h] Chughtai AA[SUP]1[/SUP], Wang Q[SUP]2[/SUP], Dung TC[SUP]3[/SUP], Macintyre CR[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We compared the rates of fever in adult subjects with laboratory-confirmed influenza and other respiratory viruses and examined the factors that predict fever in adults. Symptom data on 158 healthcare workers (HCWs) with a laboratory-confirmed respiratory virus infection were collected using standardized data collection forms from three separate studies. Overall, the rate of fever in confirmed viral respiratory infections in adult HCWs was 23?4% (37/158). Rates varied by virus: human rhinovirus (25?3%, 19/75), influenza A virus (30%, 3/10), coronavirus (28?6%, 2/7), human metapneumovirus (28?6%, 2/7), respiratory syncytial virus (14?3%, 4/28) and parainfluenza virus (8?3%, 1/12). Smoking [relative risk (RR) 4?65, 95% confidence interval (CI) 1?33-16?25] and co-infection with two or more viruses (RR 4?19, 95% CI 1?21-14?52) were significant predictors of fever. Fever is less common in adults with confirmed viral respiratory infections, including influenza, than described in children. More than 75% of adults with a viral respiratory infection do not have fever, which is an important finding for clinical triage of adult patients with respiratory infections. The accepted definition of 'influenza-like illness' includes fever and may be insensitive for surveillance when high case-finding is required. A more sensitive case definition could be used to identify adult cases, particularly in event of an emerging viral infection.


[h=4]KEYWORDS:[/h] Fever; influenza-like illness; viral infection

PMID: 27691995 DOI: 10.1017/S0950268816002181
[PubMed - as supplied by publisher]
 
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