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The changes of chest imaging and clinical features in patients with severe infection of new influenza A (H1N1)

tetano

Editor, Senior Moderator
Zhonghua Jie He He Hu Xi Za Zhi. 2010 Jun;33(6):415-418.
[The changes of chest imaging and clinical features in patients with severe infection of new influenza A (H1N1).]

[Article in Chinese]

Luo H, Fan MB, Song CP, DU CL, Bi HJ.

Department of Respiratory Medicine, the Fourth People's Hospital of Taiyuan, Shanxi Province, Taiyuan 030053, China.
Abstract

OBJECTIVE: To study the clinical features and the pulmonary imaging changes of severe cases of new influenza A (H1N1).

METHODS: This study included 10 severe cases with new influenza A (H1N1) infection in the Forth People's Hospital of Taiyuan from 20 Oct. 2009 to 22 Nov 2009.Six patients were males and 4 were females, with an average age of 19.3 years (range 5 - 41 years). The laboratory study included blood routine, blood gas analysis, liver and renal function tests, myocardium enzymology, chest radiograph and CT.

RESULTS: The prominent clinical features included fever, cough and dyspnea. The pulmonary imaging changes were varied, including ground-glass opacity, consolidation, atelectasis, fluid pneumothorax and pleural effusion, and manifestations of acute pneumonia and interstitial pneumonia simultaneously. Extensive pulmonary infiltration developed quickly, and acute lung injury (ALI) occurred in 5 patients and acute respiratory distress syndrome (ARDS) in 3 cases. Oseltamivir, oxygen therapy and antibiotic therapy were effective for improvement of the disease and final recovery of all these patients.

CONCLUSIONS: The severe cases of new influenza A (H1N1) infection has imaging manifestations of acute pneumonia and interstitial pneumonia. The disease progresses quickly and may lead to ALI/ARDS.

PMID: 20979811 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/20979811
 
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