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Text message reminders for vaccination of adolescents with chronic medical conditions: A randomized clinical trial

tetano

Editor, Senior Moderator
Vaccine. 2017 Jul 20. pii: S0264-410X(17)30920-9. doi: 10.1016/j.vaccine.2017.07.022. [Epub ahead of print]
[h=1]Text message reminders for vaccination of adolescents with chronic medical conditions: A randomized clinical trial.[/h] Hofstetter AM[SUP]1[/SUP], Barrett A[SUP]2[/SUP], Camargo S[SUP]3[/SUP], Rosenthal SL[SUP]4[/SUP], Stockwell MS[SUP]5[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Many adolescents with chronic medical conditions (CMCs) are at risk of vaccine-preventable infection, yet are frequently under-vaccinated. Text message reminders, particularly those with embedded educational information, have been shown to increase general pediatric vaccination. Their use has not been studied specifically among adolescents with CMCs.
[h=4]METHODS:[/h] Eligible parents of adolescents with CMCs receiving care at one of 4 academically-affiliated pediatric clinics and requiring human papillomavirus (first dose), influenza, and/or pneumococcal polysaccharide vaccines were randomized in 4 consecutive cohorts to receive text message vaccine reminders with or without embedded educational information ("educational" vs. "plain" arm, respectively). Educational reminders, including one interactive message, addressed infection risk, vaccine safety/efficacy, and physician recommendations. Up to 5 weekly and 2 booster reminders were sent (October 2014-January 2015). Receipt of any needed vaccine and missed vaccination opportunities by 4, 12, and 24weeks after the initial reminder were compared between arms.
[h=4]RESULTS:[/h] Of randomized parents (n=295), 175 (59.3%) were Spanish-speaking; most had adolescents with CMCs who were 13-17years (n=229; 77.6%) and publically insured (n=272; 92.5%). Baseline demographics and parental vaccine beliefs were similar between arms. More adolescents in the plain vs. educational reminder arm received any needed vaccine by 4weeks (31.9% vs. 22.7%, adjusted relative risk [aRR] 1.47, 95% CI 1.01-2.14), but not by 12 or 24weeks. Plain reminders were noted in post hoc analyses to have a greater effect than educational reminders in certain sub-populations, including 11-12year-olds and those sent the initial reminder in early fall. Fewer adolescents in the plain vs. educational reminder arm had a missed vaccination opportunity by 4weeks (10.9% vs. 41.3%; aRR 0.21, 95% CI 0.07-0.60), but not by 12 or 24weeks.
[h=4]CONCLUSION:[/h] Plain text message vaccine reminders appear to have a positive effect compared to educational ones in the short-term and for certain families.
[h=4]TRIAL REGISTRATION:[/h] NCT02231957 (www.clinicaltrials.gov).
Copyright ? 2017 Elsevier Ltd. All rights reserved.


[h=4]KEYWORDS:[/h] Adolescent; Chronic disease; Reminder/recall; Text messaging; Vaccination

PMID: 28736201 DOI: 10.1016/j.vaccine.2017.07.022
 
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