tetano
Editor, Senior Moderator
Vet Microbiol. 2014 Sep 6. pii: S0378-1135(14)00402-7. doi: 10.1016/j.vetmic.2014.08.026. [Epub ahead of print]
Temporal insight into the natural generation of a new reassortant porcine influenza virus in a swine holding.
Chiapponi C1, Baioni L2, Luppi A3, Moreno A4, Castellan A5, Foni E2.
Author information
Abstract
The influenza A virus (IAV) subtypes H1N1, H3N2 and H1N2 are the most prevalent subtypes in swine in Italy. Reassortant influenza A viruses subtypes in swine appeared in European pig population. In particular reassortant viruses carrying genome segment from the pandemic H1N1 (H1N1pdm) are reported in many European countries, including Italy. In a 1000 sows farrow-to feeder farm, in Northern Italy, we isolated 10 IAVs from recurrent episodes of respiratory disease in 45-70 days-old pigs from September 2012 to June 2013. The antigenic and genetic characterization of the swine IAV isolates showed the contemporary circulation of H1N1 avian-like and H1N1pdm strains in the first outbreak. The analysis of the viruses isolated subsequently showed the circulation of H1N1pdm IAV and then the establishment of a new previously undescribed H1N1 reassortant strain with a pandemic derived hemagglutinin gene and all the other seven segments of swine H1N1 avian-like lineage.
Copyright ? 2014 Elsevier B.V. All rights reserved.
KEYWORDS:
H1N1; Reassortant; Swine influenza A virus
PMID:
25239679
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25239679
Temporal insight into the natural generation of a new reassortant porcine influenza virus in a swine holding.
Chiapponi C1, Baioni L2, Luppi A3, Moreno A4, Castellan A5, Foni E2.
Author information
Abstract
The influenza A virus (IAV) subtypes H1N1, H3N2 and H1N2 are the most prevalent subtypes in swine in Italy. Reassortant influenza A viruses subtypes in swine appeared in European pig population. In particular reassortant viruses carrying genome segment from the pandemic H1N1 (H1N1pdm) are reported in many European countries, including Italy. In a 1000 sows farrow-to feeder farm, in Northern Italy, we isolated 10 IAVs from recurrent episodes of respiratory disease in 45-70 days-old pigs from September 2012 to June 2013. The antigenic and genetic characterization of the swine IAV isolates showed the contemporary circulation of H1N1 avian-like and H1N1pdm strains in the first outbreak. The analysis of the viruses isolated subsequently showed the circulation of H1N1pdm IAV and then the establishment of a new previously undescribed H1N1 reassortant strain with a pandemic derived hemagglutinin gene and all the other seven segments of swine H1N1 avian-like lineage.
Copyright ? 2014 Elsevier B.V. All rights reserved.
KEYWORDS:
H1N1; Reassortant; Swine influenza A virus
PMID:
25239679
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25239679