tetano
Editor, Senior Moderator
J Hosp Infect. 2018 Aug 29. pii: S0195-6701(18)30447-X. doi: 10.1016/j.jhin.2018.08.014. [Epub ahead of print]
[h=1]Targeted Management of Influenza A/B Outbreaks Incorporating the cobas? Influenza A/B & RSV into the Virology Laboratory.[/h] Lowe CF[SUP]1[/SUP], Leung V[SUP]2[/SUP], Karakas L[SUP]3[/SUP], Merrick L[SUP]3[/SUP], Lawson T[SUP]3[/SUP], Romney MG[SUP]4[/SUP], Ritchie G[SUP]4[/SUP], Payne M[SUP]2[/SUP]; PHC Infection Prevention and Control Team.
[h=3]Author information[/h]
[h=3]Abstract[/h] During the 2017/18 influenza season, our virology laboratory implemented the cobas? Influenza A/B & RSV (Roche Molecular Diagnostics, Pleasanton, CA) for influenza outbreak management in 2 scenarios: initial outbreak investigation or at outbreak conclusion to avoid prolonged measures. Twenty-seven investigations were conducted, including declaration of 11 influenza A/B outbreaks. 30% of investigations would have missed the standard batched daily laboratory-developed respiratory PCR, and delayed outbreak confirmation until the following day. The average reduction in turnaround time for influenza A/B testing was 10.2 hours. A rapid molecular PCR in specific outbreak scenarios improved timely management of influenza outbreaks.
[h=4]KEYWORDS:[/h] influenza A/B; outbreak; rapid PCR; virology
PMID: 30171885 DOI: 10.1016/j.jhin.2018.08.014
[h=1]Targeted Management of Influenza A/B Outbreaks Incorporating the cobas? Influenza A/B & RSV into the Virology Laboratory.[/h] Lowe CF[SUP]1[/SUP], Leung V[SUP]2[/SUP], Karakas L[SUP]3[/SUP], Merrick L[SUP]3[/SUP], Lawson T[SUP]3[/SUP], Romney MG[SUP]4[/SUP], Ritchie G[SUP]4[/SUP], Payne M[SUP]2[/SUP]; PHC Infection Prevention and Control Team.
[h=3]Author information[/h]
[h=3]Abstract[/h] During the 2017/18 influenza season, our virology laboratory implemented the cobas? Influenza A/B & RSV (Roche Molecular Diagnostics, Pleasanton, CA) for influenza outbreak management in 2 scenarios: initial outbreak investigation or at outbreak conclusion to avoid prolonged measures. Twenty-seven investigations were conducted, including declaration of 11 influenza A/B outbreaks. 30% of investigations would have missed the standard batched daily laboratory-developed respiratory PCR, and delayed outbreak confirmation until the following day. The average reduction in turnaround time for influenza A/B testing was 10.2 hours. A rapid molecular PCR in specific outbreak scenarios improved timely management of influenza outbreaks.
[h=4]KEYWORDS:[/h] influenza A/B; outbreak; rapid PCR; virology
PMID: 30171885 DOI: 10.1016/j.jhin.2018.08.014