Pathfinder
Editor, Senior Moderator
Publication: Bulletin of the World Health Organization; Type: Research in emergencies
Article ID: BLT.16.172080
DISCLAIMER
This paper was submitted to the Bulletin of the World Health Organization posted to the Zika
open site according to the protocol for public health emergencies for international concern as
described in Christopher Dye et al. (http://dx.doi.org/10.2471/BLT.16.170860).
The information herein is available for unrestricted use, distribution and reproduction in any
medium, provided that the original work is properly cited as indicated by the Creative Commons
Attribution 3.0 Intergovernmental Organizations licence (CC BY IGO 3.0).
RECOMMENDED CITATION
Bhide P, Kar A. Birth prevalence of microcephaly in India. [Submitted]. Bull World Health
Organ E-pub: 23 Feb 2016. doi: http://dx.doi.org/10.2471/BLT.16.172080
Birth prevalence of microcephaly in India
Prajkta Bhidea
& Anita Kara
a
Interdisciplinary School of Health Sciences, Savitribai Phule Pune University, Ganeshkhind, Pune 411
007, India.
Correspondence to Anita Kar (email: akar@unipune.ac.in).
(Submitted 19 February 2016 – Published online 23 February 2016)
Publication: Bulletin of the World Health Organization; Type: Research in emergencies
Article ID: BLT.16.172080
Abstract
Objective: To derive a baseline estimate of the birth prevalence of congenital microcephaly in
India, in the background of the suspected association with Zika virus infection
Methods: We searched Pubmed and Scopus for identifying studies reporting prevalence of
microcephaly affected births in India. Only nine studies reported data on newborns with
microcephaly among both live and stillbirths. Pooled prevalence was estimated in Review
Manager (version 5.3) software using the inverse variance method.
Findings: The pooled prevalence rate of newborns with microcephaly was 2.30 per 10 000 births
(95% CI 1.82 – 2.78) among 97 155 births reported by the nine studies.
Conclusion: The microcephaly prevalence rate was found to be similar to that reported by the
European surveillance of congenital anomalies. The need for clear case definition of
microcephaly was identified in order to limit over-reporting of cases due to diagnosis based on
subjective evaluations.
...
Full text:
http://www.who.int/bulletin/online_first/16-172080.pdf
http://www.who.int/bulletin/online_first/zika_open/en/
Article ID: BLT.16.172080
DISCLAIMER
This paper was submitted to the Bulletin of the World Health Organization posted to the Zika
open site according to the protocol for public health emergencies for international concern as
described in Christopher Dye et al. (http://dx.doi.org/10.2471/BLT.16.170860).
The information herein is available for unrestricted use, distribution and reproduction in any
medium, provided that the original work is properly cited as indicated by the Creative Commons
Attribution 3.0 Intergovernmental Organizations licence (CC BY IGO 3.0).
RECOMMENDED CITATION
Bhide P, Kar A. Birth prevalence of microcephaly in India. [Submitted]. Bull World Health
Organ E-pub: 23 Feb 2016. doi: http://dx.doi.org/10.2471/BLT.16.172080
Birth prevalence of microcephaly in India
Prajkta Bhidea
& Anita Kara
a
Interdisciplinary School of Health Sciences, Savitribai Phule Pune University, Ganeshkhind, Pune 411
007, India.
Correspondence to Anita Kar (email: akar@unipune.ac.in).
(Submitted 19 February 2016 – Published online 23 February 2016)
Publication: Bulletin of the World Health Organization; Type: Research in emergencies
Article ID: BLT.16.172080
Abstract
Objective: To derive a baseline estimate of the birth prevalence of congenital microcephaly in
India, in the background of the suspected association with Zika virus infection
Methods: We searched Pubmed and Scopus for identifying studies reporting prevalence of
microcephaly affected births in India. Only nine studies reported data on newborns with
microcephaly among both live and stillbirths. Pooled prevalence was estimated in Review
Manager (version 5.3) software using the inverse variance method.
Findings: The pooled prevalence rate of newborns with microcephaly was 2.30 per 10 000 births
(95% CI 1.82 – 2.78) among 97 155 births reported by the nine studies.
Conclusion: The microcephaly prevalence rate was found to be similar to that reported by the
European surveillance of congenital anomalies. The need for clear case definition of
microcephaly was identified in order to limit over-reporting of cases due to diagnosis based on
subjective evaluations.
...
Full text:
http://www.who.int/bulletin/online_first/16-172080.pdf
http://www.who.int/bulletin/online_first/zika_open/en/