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Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs

tetano

Editor, Senior Moderator
Data Brief. 2019 Sep 28;27:104576. doi: 10.1016/j.dib.2019.104576. eCollection 2019 Dec. [h=1]Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs.[/h]
Canini L[SUP]1[/SUP], Everett HE[SUP]2[/SUP], Aramouni M[SUP]3[/SUP], Coward V[SUP]2[/SUP], Ramsay A[SUP]2[/SUP], Kelly M[SUP]2[/SUP], Morgan S[SUP]4[/SUP], Tchilian E[SUP]4[/SUP], Gilbert S[SUP]3[/SUP], Charleston B[SUP]4[/SUP], Brown IH[SUP]2[/SUP], Brookes SM[SUP]2[/SUP], Woolhouse MEJ[SUP]1[/SUP].
[h=3]Author information[/h] 1 University of Edinburgh, University of Edinburgh, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK. 2 Virology Department, Animal and Plant Health Agency (APHA-Weybridge), New Haw, Addlestone, KT15 3NB, UK. 3 The Jenner Institute, University of Oxford, ORCRB, Roosevelt Drive, Oxford, OX3 7DQ, UK. 4 The Pirbright Institute, Ash Road, Pirbright, Woking, GU24 0NF, UK.

[h=3]Abstract[/h] A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics.
Crown Copyright ? 2019 Published by Elsevier Inc.


[h=4]KEYWORDS:[/h] Pandemic 2009 swine influenza a virus; Statistical modelling RRT-qPCR; Viral kinetics; Whole inactivated vaccine

PMID: 31687431 PMCID: PMC6820103 DOI: 10.1016/j.dib.2019.104576
Free PMC Article
 
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