tetano
Editor, Senior Moderator
Singapore Med J
. 2020 Sep 21.
doi: 10.11622/smedj.2020142. Online ahead of print.
Radiographic features of COVID-19 based on an initial cohort of 96 patients in Singapore
Hau Wei Khoo[SUP] 1 [/SUP], Terrence Chi Hong Hui[SUP] 1 [/SUP], Salahudeen Mohamed Haja Mohideen[SUP] 2 [/SUP], Yeong Shyan Lee[SUP] 1 [/SUP], Charlene Jin Yee Liew[SUP] 3 4 [/SUP], Shawn Shi Xian Kok[SUP] 5 [/SUP], Barnaby Edward Young[SUP] 6 7 [/SUP], Sean Wei Xiang Ong[SUP] 6 7 [/SUP], Shirin Kalimuddin[SUP] 4 8 [/SUP], Seow Yen Tan[SUP] 9 [/SUP], Jiashen Loh[SUP] 10 [/SUP], Lai Peng Chan[SUP] 2 11 [/SUP], Angeline Choo Choo Poh[SUP] 3 [/SUP], Steven Bak Siew Wong[SUP] 5 [/SUP], Yee-Sin Leo[SUP] 6 7 11 12 13 [/SUP], David Chien Lye[SUP] 6 7 11 13 [/SUP], Gregory Jon Leng Kaw[SUP] 1 [/SUP], Cher Heng Tan[SUP] 1 13 [/SUP]
Affiliations
Abstract
Introduction: Chest radiographs (CXR) are widely used for the screening and management of the coronavirus disease 2019 (COVID-19). This paper determinates the radiographic features of COVID-19 based on an initial national cohort of patients.
Methods: This is a retrospective review of swab-positive COVID-19 patients admitted to four different hospitals in Singapore between 22 January and 9 March 2020. Initial and follow-up CXR were reviewed by three experienced radiologists to identify the predominant pattern and distribution of lung parenchymal abnormalities.
Results: In total, 347 CXR of 96 patients were reviewed. Initial CXR were abnormal in 41 out of 96 patients (42.7%). The mean time from onset of symptoms to CXR abnormality was 5.3 (range 1-21) days. The predominant pattern of lung abnormality was ground-glass opacity on initial CXR (51.2%) and consolidation on follow-up CXR (51.0%). Multifocal bilateral abnormalities in mixed central and peripheral distribution were seen in 63.4% and 59.2% of abnormal initial and follow-up CXR, respectively. The lower zones were involved in 90.2% of the initial CXR and 93.9% of the follow-up CXR.
Conclusion: In a cohort of swab-positive patients, including those identified from contact tracing, we found the incidence of CXR abnormality to be lower than previously reported. The most common pattern was ground-glass opacity or consolidation, but mixed central and peripheral involvement was more common than peripheral involvement alone.
Keywords: SARS-CoV-2; chest radiographs; coronavirus disease 2019.
. 2020 Sep 21.
doi: 10.11622/smedj.2020142. Online ahead of print.
Radiographic features of COVID-19 based on an initial cohort of 96 patients in Singapore
Hau Wei Khoo[SUP] 1 [/SUP], Terrence Chi Hong Hui[SUP] 1 [/SUP], Salahudeen Mohamed Haja Mohideen[SUP] 2 [/SUP], Yeong Shyan Lee[SUP] 1 [/SUP], Charlene Jin Yee Liew[SUP] 3 4 [/SUP], Shawn Shi Xian Kok[SUP] 5 [/SUP], Barnaby Edward Young[SUP] 6 7 [/SUP], Sean Wei Xiang Ong[SUP] 6 7 [/SUP], Shirin Kalimuddin[SUP] 4 8 [/SUP], Seow Yen Tan[SUP] 9 [/SUP], Jiashen Loh[SUP] 10 [/SUP], Lai Peng Chan[SUP] 2 11 [/SUP], Angeline Choo Choo Poh[SUP] 3 [/SUP], Steven Bak Siew Wong[SUP] 5 [/SUP], Yee-Sin Leo[SUP] 6 7 11 12 13 [/SUP], David Chien Lye[SUP] 6 7 11 13 [/SUP], Gregory Jon Leng Kaw[SUP] 1 [/SUP], Cher Heng Tan[SUP] 1 13 [/SUP]
Affiliations
- PMID: 33047143
- DOI: 10.11622/smedj.2020142
Abstract
Introduction: Chest radiographs (CXR) are widely used for the screening and management of the coronavirus disease 2019 (COVID-19). This paper determinates the radiographic features of COVID-19 based on an initial national cohort of patients.
Methods: This is a retrospective review of swab-positive COVID-19 patients admitted to four different hospitals in Singapore between 22 January and 9 March 2020. Initial and follow-up CXR were reviewed by three experienced radiologists to identify the predominant pattern and distribution of lung parenchymal abnormalities.
Results: In total, 347 CXR of 96 patients were reviewed. Initial CXR were abnormal in 41 out of 96 patients (42.7%). The mean time from onset of symptoms to CXR abnormality was 5.3 (range 1-21) days. The predominant pattern of lung abnormality was ground-glass opacity on initial CXR (51.2%) and consolidation on follow-up CXR (51.0%). Multifocal bilateral abnormalities in mixed central and peripheral distribution were seen in 63.4% and 59.2% of abnormal initial and follow-up CXR, respectively. The lower zones were involved in 90.2% of the initial CXR and 93.9% of the follow-up CXR.
Conclusion: In a cohort of swab-positive patients, including those identified from contact tracing, we found the incidence of CXR abnormality to be lower than previously reported. The most common pattern was ground-glass opacity or consolidation, but mixed central and peripheral involvement was more common than peripheral involvement alone.
Keywords: SARS-CoV-2; chest radiographs; coronavirus disease 2019.