tetano
Editor, Senior Moderator
Intern Med. 2010;49(15):1667-70. Epub 2010 Aug 2.
Severe Pneumonia Caused by a Novel Influenza A (H1N1) Virus in an Asymptomatic Emphysematous Smoker.
Ozawa H, Asai S, Jin G, Hasunuma Y, Tanaka C, Ikeda T, Kimura M, Ueda A, Yamashita T, Miyachi H.
Department of Internal Medicine, Tokai University School of Medicine.
Abstract
A 49-year-old female presented with diarrhea and a high fever followed by progressive dyspnea. Until this presentation, she had been healthy except for chronic dyspepsia and diarrhea. She had a smoking habit of 15 pack-years. Laboratory tests revealed lymphopenia, hypoalbuminemia and hypogammaglobulinemia. A rapid influenza test in combination with an RT-PCR assay revealed the presence of the novel influenza A (H1N1) virus. Chest computed tomography revealed centrilobular emphysema. This report suggests that regular smoking may become a risk for severe pneumonia in patients presenting with the novel influenza A (H1N1) virus, when accompanying asymptomatic emphysema is combined with other problems such as hypoalbuminemia and hypogammaglobulinemia.
PMID: 20686312 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20686312
Severe Pneumonia Caused by a Novel Influenza A (H1N1) Virus in an Asymptomatic Emphysematous Smoker.
Ozawa H, Asai S, Jin G, Hasunuma Y, Tanaka C, Ikeda T, Kimura M, Ueda A, Yamashita T, Miyachi H.
Department of Internal Medicine, Tokai University School of Medicine.
Abstract
A 49-year-old female presented with diarrhea and a high fever followed by progressive dyspnea. Until this presentation, she had been healthy except for chronic dyspepsia and diarrhea. She had a smoking habit of 15 pack-years. Laboratory tests revealed lymphopenia, hypoalbuminemia and hypogammaglobulinemia. A rapid influenza test in combination with an RT-PCR assay revealed the presence of the novel influenza A (H1N1) virus. Chest computed tomography revealed centrilobular emphysema. This report suggests that regular smoking may become a risk for severe pneumonia in patients presenting with the novel influenza A (H1N1) virus, when accompanying asymptomatic emphysema is combined with other problems such as hypoalbuminemia and hypogammaglobulinemia.
PMID: 20686312 [PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/20686312