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Severe influenza A (H1N1) in late pregnancy: a case report

tetano

Editor, Senior Moderator
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2019 Dec;31(12):1545-1546. doi: 10.3760/cma.j.issn.2095-4352.2019.12.023. [h=1][Severe influenza A (H1N1) in late pregnancy: a case report].[/h]
[Article in Chinese]

Zhang R[SUP]1[/SUP], Yue J[SUP]1[/SUP], Zhu W[SUP]1[/SUP], Liu O[SUP]1[/SUP], Du L[SUP]2[/SUP], Huang Q[SUP]1[/SUP], Ma R[SUP]3[/SUP], Wan L[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Pregnancy has increased susceptibility to H1N1 influenza virus infection. Maternal influenza infection is associated with increased risk of morbidity and mortality. A case of influenza A (H1N1) during late pregnancy (pregnancy 1, birth 0, pregnancy 30[SUP]+2[/SUP] weeks) was admitted to the Second Affiliated Hospital of Kunming Medical University on December 16th, 2018. The patient was set on mechanical ventilation with a FiO[SUB]2[/SUB] of 1.0, a positive end-expiratory pressure (PEEP) of 15 cmH[SUB]2[/SUB]O (1 cmH[SUB]2[/SUB]O = 0.098 kPa), and a tidal volume of 4-6 mL/kg (ideal body weight). However the pulse oxygen saturation (SpO[SUB]2[/SUB]) could only be maintained at about 0.85. The disease was controlled by the treatments of anti-infection, mechanical ventilation, immune therapy, nutritional support, preventive anticoagulant treatment by heparin sodium, adequate negative fluid balance, and other organ support therapy. This article introduced the treatment process of the patient in detail, and provided experience for clinical treatment.


PMID: 32029047 DOI: 10.3760/cma.j.issn.2095-4352.2019.12.023
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