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Seroprevalence survey of avian influenza A(H5N1) among live poultry market workers in northern Viet Nam, 2011

tetano

Editor, Senior Moderator
Western Pac Surveill Response J. 2014 Nov 18;5(4):21-26.
[h=1]Seroprevalence survey of avian influenza A(H5N1) among live poultry market workers in northern Viet Nam, 2011.[/h] Dung TC[SUP]1[/SUP], Dinh PN[SUP]1[/SUP], Nam VS[SUP]2[/SUP], Tan LM[SUP]1[/SUP], Hang NL[SUP]1[/SUP], Thanh LT[SUP]1[/SUP], Mai LQ[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]OBJECTIVE:[/h] Highly pathogenic avian influenza A(H5N1) is endemic in poultry in Viet Nam. The country has experienced the third highest number of human infections with influenza A(H5N1) in the world. A study in Hanoi in 2001, before the epizootic that was identified in 2003, found influenza A(H5N1) specific antibodies in 4% of poultry market workers (PMWs). We conducted a seroprevalence survey to determine the seroprevalence of antibodies to influenza A(H5N1) among PMWs in Hanoi, Thaibinh and Thanhhoa provinces.
[h=4]METHODS:[/h] We selected PMWs from five markets, interviewed them and collected blood samples. These were then tested using a horse haemagglutination inhibition assay and a microneutralization assay with all three clades of influenza A(H5N1) viruses that have circulated in Viet Nam since 2004.
[h=4]RESULTS:[/h] The overall seroprevalence was 6.1% (95% confidence interval: 4.6-8.3). The highest proportion (7.2%) was found in PMWs in Hanoi, and the majority of seropositive subjects (70.3%) were slaughterers or sellers of poultry.
[h=4]DISCUSSION:[/h] The continued circulation and evolution of influenza A(H5N1) requires comprehensive surveillance of both human and animal sites throughout the country with follow-up studies on PMWs to estimate the risk of avian-human transmission of influenza A(H5N1) in Viet Nam.


PMID: 25685601 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25685601
 
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