tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2020 Mar 10. doi: 10.1111/irv.12736. [Epub ahead of print] [h=1]Seroprevalence of H7N9 infection among humans: A systematic review and meta-analysis.[/h]
Wang Q[SUP]1,[/SUP][SUP]2[/SUP], Xu K[SUP]3[/SUP], Xie W[SUP]1,[/SUP][SUP]2[/SUP], Yang L[SUP]1,[/SUP][SUP]2[/SUP], Chen H[SUP]4[/SUP], Shi N[SUP]1,[/SUP][SUP]2[/SUP], Bao C[SUP]3[/SUP], Huang H[SUP]3[/SUP], Zhang X[SUP]3[/SUP], Liao Y[SUP]5[/SUP], Jin H[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In spring 2013, a novel avian-origin influenza A (H7N9) virus emerged in mainland China. The burden of H7N9 infection was estimated based on systematic review and meta-analysis. The systematic search for available literature was conducted using Chinese and English databases. We calculated the pooled seroprevalence of H7N9 infection and its 95% confidence interval by using Freeman-Tukey double arcsine transformation. Out of 16 890 records found using Chinese and English databases, 54 articles were included in the meta-analysis. These included studies of a total of 64 107 individuals. The pooled seroprevalence of H7N9 infection among humans was 0.122% (95% CI: 0.023, 0.275). In high-risk populations, the highest pooled seroprevalence was observed among close contacts (1.075%, 95% CI: 0.000, 4.357). The seroprevalence among general population was (0.077%, 95% CI: 0.011, 0.180). Our study discovered that asymptomatic infection of H7N9 virus did occur, even if the seroprevalence among humans was low.
? 2020 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] H7N9; influenza A; meta-analysis; seroprevalence; systematic review
PMID: 32157809 DOI: 10.1111/irv.12736
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Wang Q[SUP]1,[/SUP][SUP]2[/SUP], Xu K[SUP]3[/SUP], Xie W[SUP]1,[/SUP][SUP]2[/SUP], Yang L[SUP]1,[/SUP][SUP]2[/SUP], Chen H[SUP]4[/SUP], Shi N[SUP]1,[/SUP][SUP]2[/SUP], Bao C[SUP]3[/SUP], Huang H[SUP]3[/SUP], Zhang X[SUP]3[/SUP], Liao Y[SUP]5[/SUP], Jin H[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In spring 2013, a novel avian-origin influenza A (H7N9) virus emerged in mainland China. The burden of H7N9 infection was estimated based on systematic review and meta-analysis. The systematic search for available literature was conducted using Chinese and English databases. We calculated the pooled seroprevalence of H7N9 infection and its 95% confidence interval by using Freeman-Tukey double arcsine transformation. Out of 16 890 records found using Chinese and English databases, 54 articles were included in the meta-analysis. These included studies of a total of 64 107 individuals. The pooled seroprevalence of H7N9 infection among humans was 0.122% (95% CI: 0.023, 0.275). In high-risk populations, the highest pooled seroprevalence was observed among close contacts (1.075%, 95% CI: 0.000, 4.357). The seroprevalence among general population was (0.077%, 95% CI: 0.011, 0.180). Our study discovered that asymptomatic infection of H7N9 virus did occur, even if the seroprevalence among humans was low.
? 2020 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
[h=4]KEYWORDS:[/h] H7N9; influenza A; meta-analysis; seroprevalence; systematic review
PMID: 32157809 DOI: 10.1111/irv.12736
Free full text