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Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza

tetano

Editor, Senior Moderator
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine

Methods: We focused on the H1N1 pandemic influenza vaccine Pandemrix(R) and applied a self reporting questionnaire in a population of healthcare workers (HCWs) and medical students at a major university hospital.

Results: In total, 4337 individuals were vaccinated, consisting of 3808 HCWs and 529 medical students.

The vaccination rate of the employees was higher than 40%.The majority of individuals were vaccinated in November 2009. In total, 291 of the 4337 vaccinations were reported to lead to one or more adverse reactions (6.7%).

Local reactions were reported in 3.8%, myalgia and arthralgia in 3.7%, fatigue in 3.7%, headache in 3.1%.

Conclusions: Our data together with available data from several national and international institutions points to a safe pandemic influenza vaccine.

Author: Harald BiasDavid QuarcooClaus Meier-WronskiSabine WickerJoachim SeyboldAlbert NienhausDavid GronebergAndres de Roux
Credits/Source: BMC Research Notes 2011, 4:297



Published on: 2011-08-17

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