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Seattle 1918 vaccine

AlaskaDenise

AlaskaDenise

In Memoriam
I ran across this old paper about the 1918 influenza Seattle pandemic and this sentence was a surprise to me:
The Seattle Department of Health and Sanitation and doctors at the Puget Sound Naval Shipyard developed a vaccine and ordered that all shipyard workers be vaccinated. Of the 10,000 persons vaccinated, none developed influenza.
Click to expand...


Further reading found:
The city concocted its own flu vaccine, based on bacteria found in the dead, and inoculated thousands. Yet the serum did nothing to ward off or lessen the disease.
Click to expand...
source: http://seattletimes.nwsource.com/pacificnw/2004/1024/cover.html​

Does anyone have any further information on this vaccine?​

Apparently this was tried in several places and more details might be interesting. Why did this work for some people and not others? Can anything be replicated today?​

This may be the "plasma" shot some have referenced.
.​
 
Re: Seattle 1918 vaccine

Good evening AD,

Concerning the 1918 vaccines outreach and empirical trials, most of the data in the last Century had fallen into the slow mo take it off the university shelves mode.

Since this was not an imperative executive order a lot of records had subsisted.

On the Internet I have not found has much as I found in old medical Universitarian Library.

There where quite a few datas in my Trail.

As Joe Thornton express it eloquently in his answered to GR in one of GR push, Joe express, cause and effect first and then maybe whose is guilty.

I have personnaly saw, some of Président Wison daily notes at the Congress in Washington, but again do not forget that the man became sick indeed by the Spanish Lady.

Hope this has seeds,

Snowy
 
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Re: Seattle 1918 vaccine

AD this from Australia
1919 Influenza Epidemic
CSL's first challenge is the Influenza Epidemic of 1919 - the "Spanish 'Flu". When the epidemic reaches Australia in January 1919, public health authorities respond by closing cinemas, theatres, racecourses and schools. Masks are required of anyone moving through the streets. Schools and kindergartens - even Melbourne's Exhibition Building - are turned into makeshift hospitals.
CSL's staff numbers are temporarily tripled as the organisation produces 3 million doses of a mixed bacterial vaccine in an attempt to combat the disease.
Click to expand...
http://www.toxinology.com/fusebox.cfm?staticaction=generic_static_files/avp-csl-01.html


Wonder if they used the vaccine.
Australias fatality rate was?
 
Re: Seattle 1918 vaccine

(H?mophilus
influenz?, Pfeiffer 1891),
probably this one, wich was isolated in some cases ( surinfection )
 
Re: Seattle 1918 vaccine

> Of the 10,000 persons vaccinated, none developed influenza.

this is still a bit strange and hard to believe
 
Re: Seattle 1918 vaccine

Early understanding was that Bacillus influenzae (now named Haemophilus influenzae)was the causitive agent of influenza. Streptococcus pneumoniae (pneumococci) was recognized as a causitive agent of many of the bacterial pneumonias that followed acute infection and were associated with more delayed mortality events.

New York scientists developed a mixed bacterial vaccine that included B. influenzae, multiple pneumococci strains and hemolytic streptococcus strains. Ther are also reports of limited use of serum from survivors.

These vaccinations were used primarily among military populations. They had mixed reports of efficacy.

I cannot find specific information about Seattle, but I suspect they may have followed NY's lead in vaccine development/production.
 
Re: Seattle 1918 vaccine

I can't believe that vaccine prevented 100% of infections from
these 10000. Maybe they became immune earlier through
low-dose exposure with sailors ?!
Reminds me also to the mysterial failure to infect "volunteers"
in Boston and San Francisco.

What did protect those people ?
 
Re: Seattle 1918 vaccine

"The disease disappeared from around the world almost as fast as it appeared and it has not reappeared since."

10,000 doses of vaccine are not produced overnight. The article does not state when the vaccine was administered. It is possible that the vaccine was administered after the epidemic passed OR that the media spin of influenza news was in full operation.

I am not aware of ANY vaccine that has 100% efficacy.
 
Re: Seattle 1918 vaccine

I'm not even aware of any US-group of people as large as 10000
that escaped 1918 panflu, vaccinated or not.
 
Re: Seattle 1918 vaccine

It is possible that the vaccine was administered after the epidemic passed OR that the media spin of influenza news was in full operation.
Click to expand...
Highly likely. If we think our current media is not fully informed, just imagine what they were like in 1918, when even the scientists knew very little. :D

Still, there were instances where blood products were administered and they apparently worked by utilizing antibodies. One of our medical professional members said that it is possibly to extract serum from survivors that contains H5N1 antibodies.

It would be interesting if someone was able to study all these attempts utilizing survivor blood and come to some conclusions. Although, I imagine there is little data available.

.
 
Re: Seattle 1918 vaccine

AD, I have work narroly with an Historical Foundation, they have kept local papers, it is in those ones that I have found many surprises.

Snowy
 
Re: Seattle 1918 vaccine

This could be an interesting read. Date is a a bit out, but still, viruses were new. Might also reference 1918
http://www.austehc.unimelb.edu.au/guides/burn/FMBS0002.htm

<table border="0" cellpadding="5"><tbody><tr valign="top"><td nowrap="nowrap">2-81 </td> <td> Laboratory Notebook - Influenza Virus Research 1937-1938 [Two files]
</td> </tr> <tr valign="top"> <td>
</td> <td> <small>Photocopy of notebook housed in Department of Microbiology, University of Melbourne. Includes research summaries 1937-1938, experimental records 1937-1940, notes on future research, influenza, Q-fever, polio and others. Front pages
</small> Creator Frank Macfarlane Burnet
Date range February 1937 - August 1940 Quantity 2.4 cm, 1 file
Inventory Identifier 02/081 Box Number 14 Series 2 </td> </tr> <tr valign="top"> <td nowrap="nowrap"> 2-82 </td> <td> Laboratory Notebook - Influenza Virus Research 1937-1938 [Second File]
</td> </tr> <tr valign="top"> <td>
</td> <td> <small>Photocopy of rear pages of notebook
</small> Creator Frank Macfarlane Burnet
Date range 1937 - 1940 Quantity 0.3 cm, 1 file
Inventory Identifier 02/082 Box Number 14 Series 2 </td></tr></tbody></table>
 
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