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Seasonal influenza vaccination during pregnancy may reduce risk of stillbirth

tetano

Editor, Senior Moderator
Seasonal influenza vaccination may guard against stillbirth, a new study published in Clinical Infectious Diseases and available online suggests. Researchers in Western Australia analyzed data from nearly 60,000 births that occurred during the southern hemisphere's 2012 and 2013 seasonal influenza epidemics, and found that women who received the trivalent influenza vaccine during pregnancy were 51 percent less likely to experience a stillbirth than unvaccinated mothers.



The retrospective study used midwives' records to examine a cohort of 58,008 births: 52,932 to mothers who had not received the vaccine and 5,076 to mothers who had been vaccinated during pregnancy. All births took place in Western Australia between April of 2012 and December of 2013. The adjusted risk of stillbirth among vaccinated mothers was 51 percent lower than the risk among women who had not been vaccinated.
Researchers also observed that stillbirth rates increased after periods of influenza virus circulation and decreased during the months prior to the influenza season, although the seasonal differences were not statistically significant. The study's results are consistent with those of a 2000 study in Switzerland that recorded increased incidence of stillbirth in relation to the northern hemisphere's influenza season, as well as with similar research conducted during the influenza A/H1N1 pandemic.

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http://medicalxpress.com/news/2016-03-seasonal-influenza-vaccination-pregnancy-stillbirth.html
 
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