tetano
Editor, Senior Moderator
Sci Rep
. 2020 Aug 31;10(1):14296.
doi: 10.1038/s41598-020-71275-5.
Novel reassortant swine H3N2 influenza A viruses in Germany
Roland Zell[SUP] 1 [/SUP], Marco Groth[SUP] 2 [/SUP], Andi Krumbholz[SUP] 3 4 [/SUP], Jeannette Lange[SUP] 3 5 [/SUP], Anja Philipps[SUP] 3 6 [/SUP], Ralf D?rrwald[SUP] 3 7 [/SUP]
Affiliations
Abstract
Analysis of 228 H3N2 swine influenza A virus isolates collected between 2003 and 2015 in Germany revealed important changes in molecular epidemiology. The data indicate that a novel reassortant, Rietberg/2014-like swine H3N2, emerged in February 2014 in Northern Germany. It is comprised of a hemagglutinin gene of seasonal H3N2 (A/Denmark/129/2005-like), a neuraminidase gene of Emmelsbuell/2009-like swine H1N2 and the internal gene cassette of pandemic H1N1 viruses. Together with Danish swine H3N2 strains of 2013-2015 with identical genome layout, the Rietberg/2014-like viruses represent a second swine H3N2 lineage which cocirculates with a variant of the Gent/1984-like swine H3N2 lineage. This variant, named Gent1984/Diepholz-like swine H3N2, has a Gent/1984-like HA and a Diepholz/2008-like NA; the origin of the internal gene cassette likely derived from avian-like swine H1N1. The first isolate of the Gent1984/Diepholz reassortant emerged in Northern Germany in September 2011 whereas the last German Gent/1984-like isolate was collected in October 2011.
. 2020 Aug 31;10(1):14296.
doi: 10.1038/s41598-020-71275-5.
Novel reassortant swine H3N2 influenza A viruses in Germany
Roland Zell[SUP] 1 [/SUP], Marco Groth[SUP] 2 [/SUP], Andi Krumbholz[SUP] 3 4 [/SUP], Jeannette Lange[SUP] 3 5 [/SUP], Anja Philipps[SUP] 3 6 [/SUP], Ralf D?rrwald[SUP] 3 7 [/SUP]
Affiliations
- PMID: 32868846
- DOI: 10.1038/s41598-020-71275-5
Abstract
Analysis of 228 H3N2 swine influenza A virus isolates collected between 2003 and 2015 in Germany revealed important changes in molecular epidemiology. The data indicate that a novel reassortant, Rietberg/2014-like swine H3N2, emerged in February 2014 in Northern Germany. It is comprised of a hemagglutinin gene of seasonal H3N2 (A/Denmark/129/2005-like), a neuraminidase gene of Emmelsbuell/2009-like swine H1N2 and the internal gene cassette of pandemic H1N1 viruses. Together with Danish swine H3N2 strains of 2013-2015 with identical genome layout, the Rietberg/2014-like viruses represent a second swine H3N2 lineage which cocirculates with a variant of the Gent/1984-like swine H3N2 lineage. This variant, named Gent1984/Diepholz-like swine H3N2, has a Gent/1984-like HA and a Diepholz/2008-like NA; the origin of the internal gene cassette likely derived from avian-like swine H1N1. The first isolate of the Gent1984/Diepholz reassortant emerged in Northern Germany in September 2011 whereas the last German Gent/1984-like isolate was collected in October 2011.