tetano
Editor, Senior Moderator
Health Serv Res. 2017 Dec;52 Suppl 2:2307-2330. doi: 10.1111/1475-6773.12786.
[h=1]School-Based Influenza Vaccination: Health and Economic Impact of Maine's 2009 Influenza Vaccination Program.[/h] Basurto-D?vila R[SUP]1[/SUP], Meltzer MI[SUP]2[/SUP], Mills DA[SUP]3[/SUP], Beeler Asay GR[SUP]2[/SUP], Cho BH[SUP]2[/SUP], Graitcer SB[SUP]2[/SUP], Dube NL[SUP]4[/SUP], Thompson MG[SUP]2[/SUP], Patel SA[SUP]2[/SUP], Peasah SK[SUP]5[/SUP], Ferdinands JM[SUP]2[/SUP], Gargiullo P[SUP]2[/SUP], Messonnier M[SUP]2[/SUP], Shay DK[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVE:[/h] To estimate the societal economic and health impacts of Maine's school-based influenza vaccination (SIV) program during the 2009 A(H1N1) influenza pandemic.
[h=4]DATA SOURCES:[/h] Primary and secondary data covering the 2008-09 and 2009-10 influenza seasons.
[h=4]STUDY DESIGN:[/h] We estimated weekly monovalent influenza vaccine uptake in Maine and 15 other states, using difference-in-difference-in-differences analysis to assess the program's impact on immunization among six age groups. We also developed a health and economic Markov microsimulation model and conducted Monte Carlo sensitivity analysis.
[h=4]DATA COLLECTION:[/h] We used national survey data to estimate the impact of the SIV program on vaccine coverage. We used primary data and published studies to develop the microsimulation model.
[h=4]PRINCIPAL FINDINGS:[/h] The program was associated with higher immunization among children and lower immunization among adults aged 18-49 years and 65 and older. The program prevented 4,600 influenza infections and generated $4.9 million in net economic benefits. Cost savings from lower adult vaccination accounted for 54 percent of the economic gain. Economic benefits were positive in 98 percent of Monte Carlo simulations.
[h=4]CONCLUSIONS:[/h] SIV may be a cost-beneficial approach to increase immunization during pandemics, but programs should be designed to prevent lower immunization among nontargeted groups.
? Health Research and Educational Trust.
[h=4]KEYWORDS:[/h] Pandemics; economic evaluation; immunization
PMID: 29130266 DOI: 10.1111/1475-6773.12786
[h=1]School-Based Influenza Vaccination: Health and Economic Impact of Maine's 2009 Influenza Vaccination Program.[/h] Basurto-D?vila R[SUP]1[/SUP], Meltzer MI[SUP]2[/SUP], Mills DA[SUP]3[/SUP], Beeler Asay GR[SUP]2[/SUP], Cho BH[SUP]2[/SUP], Graitcer SB[SUP]2[/SUP], Dube NL[SUP]4[/SUP], Thompson MG[SUP]2[/SUP], Patel SA[SUP]2[/SUP], Peasah SK[SUP]5[/SUP], Ferdinands JM[SUP]2[/SUP], Gargiullo P[SUP]2[/SUP], Messonnier M[SUP]2[/SUP], Shay DK[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]OBJECTIVE:[/h] To estimate the societal economic and health impacts of Maine's school-based influenza vaccination (SIV) program during the 2009 A(H1N1) influenza pandemic.
[h=4]DATA SOURCES:[/h] Primary and secondary data covering the 2008-09 and 2009-10 influenza seasons.
[h=4]STUDY DESIGN:[/h] We estimated weekly monovalent influenza vaccine uptake in Maine and 15 other states, using difference-in-difference-in-differences analysis to assess the program's impact on immunization among six age groups. We also developed a health and economic Markov microsimulation model and conducted Monte Carlo sensitivity analysis.
[h=4]DATA COLLECTION:[/h] We used national survey data to estimate the impact of the SIV program on vaccine coverage. We used primary data and published studies to develop the microsimulation model.
[h=4]PRINCIPAL FINDINGS:[/h] The program was associated with higher immunization among children and lower immunization among adults aged 18-49 years and 65 and older. The program prevented 4,600 influenza infections and generated $4.9 million in net economic benefits. Cost savings from lower adult vaccination accounted for 54 percent of the economic gain. Economic benefits were positive in 98 percent of Monte Carlo simulations.
[h=4]CONCLUSIONS:[/h] SIV may be a cost-beneficial approach to increase immunization during pandemics, but programs should be designed to prevent lower immunization among nontargeted groups.
? Health Research and Educational Trust.
[h=4]KEYWORDS:[/h] Pandemics; economic evaluation; immunization
PMID: 29130266 DOI: 10.1111/1475-6773.12786