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Scand J Immunol . From Spike to Strike: SARS-CoV-2 mRNA Vaccines Sensitise Tumours to PD-1/PD-L1 Blockade

tetano

tetano

Editor, Senior Moderator
Scand J Immunol


. 2025 Dec;102(6):e70079.
doi: 10.1111/sji.70079. From Spike to Strike: SARS-CoV-2 mRNA Vaccines Sensitise Tumours to PD-1/PD-L1 Blockade

Julian Jamie Freen-van Heeren[SUP] 1 [/SUP]



Affiliations
Abstract

This letter comments on work by Grippin et al. demonstrating that SARS-CoV-2 mRNA vaccines can reprogram the tumour microenvironment and enhance PD-1/PD-L1 blockade, suggesting broader implications for mRNA-driven immune activation in cancer therapy.


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