tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2014 Jan 31. doi: 10.1111/irv.12230. [Epub ahead of print]
Revised and updated nomenclature for highly pathogenic avian influenza A (H5N1) viruses.
World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization (WHO/OIE/FAO) H5N1 Evolution Working Group.
Abstract
The divergence of the hemagglutinin gene of A/goose/Guangdong/1/1996-lineage H5N1 viruses during 2011 and 2012 (807 new sequences collected through December 31, 2012) was analyzed by phylogenetic and p-distance methods to define new clades using the pre-established nomenclature system. Eight new clade designations were recommended based on division of clade 1?1 (Mekong River Delta), 2?1?3?2 (Indonesia), 2?2?2 (India/Bangladesh), 2?2?1?1 (Egypt/Israel), and 2?3?2?1 (Asia). A simplification to the previously defined criteria, which adds a letter rather than number to the right-most digit of fifth-order clades, was proposed to facilitate this and future updates.
? 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
KEYWORDS:
H5N1, hemagglutinin, highly pathogenic avian influenza, molecular epidemiology, nomenclature, phylogenetics, viral evolution
PMID:
24483237
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24483237
Revised and updated nomenclature for highly pathogenic avian influenza A (H5N1) viruses.
World Health Organization/World Organisation for Animal Health/Food and Agriculture Organization (WHO/OIE/FAO) H5N1 Evolution Working Group.
Abstract
The divergence of the hemagglutinin gene of A/goose/Guangdong/1/1996-lineage H5N1 viruses during 2011 and 2012 (807 new sequences collected through December 31, 2012) was analyzed by phylogenetic and p-distance methods to define new clades using the pre-established nomenclature system. Eight new clade designations were recommended based on division of clade 1?1 (Mekong River Delta), 2?1?3?2 (Indonesia), 2?2?2 (India/Bangladesh), 2?2?1?1 (Egypt/Israel), and 2?3?2?1 (Asia). A simplification to the previously defined criteria, which adds a letter rather than number to the right-most digit of fifth-order clades, was proposed to facilitate this and future updates.
? 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.
KEYWORDS:
H5N1, hemagglutinin, highly pathogenic avian influenza, molecular epidemiology, nomenclature, phylogenetics, viral evolution
PMID:
24483237
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24483237