tetano
Editor, Senior Moderator
J Virol. 2015 Sep 23. pii: JVI.02164-15. [Epub ahead of print]
[h=1]Replication competent influenza B reporter viruses as tools for screening antivirals and antibodies.[/h] Fulton BO[SUP]1[/SUP], Palese P[SUP]2[/SUP], Heaton NS[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B virus is a human pathogen responsible for significant health and economic burden. Research into this pathogen has been limited by the lack of reporter viruses. Here we describe the development of both a replication-competent fluorescent and bioluminescent influenza B reporter virus. Furthermore, we demonstrate these reporter viruses can be used to quickly monitor viral growth and permit the rapid screening of antiviral compounds and neutralizing antibodies.
Copyright ? 2015, American Society for Microbiology. All Rights Reserved.
PMID: 26401044 [PubMed - as supplied by publisher]
[h=1]Replication competent influenza B reporter viruses as tools for screening antivirals and antibodies.[/h] Fulton BO[SUP]1[/SUP], Palese P[SUP]2[/SUP], Heaton NS[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza B virus is a human pathogen responsible for significant health and economic burden. Research into this pathogen has been limited by the lack of reporter viruses. Here we describe the development of both a replication-competent fluorescent and bioluminescent influenza B reporter virus. Furthermore, we demonstrate these reporter viruses can be used to quickly monitor viral growth and permit the rapid screening of antiviral compounds and neutralizing antibodies.
Copyright ? 2015, American Society for Microbiology. All Rights Reserved.
PMID: 26401044 [PubMed - as supplied by publisher]