tetano
Editor, Senior Moderator
J Infect Dis. 2019 May 20. pii: jiz266. doi: 10.1093/infdis/jiz266. [Epub ahead of print]
[h=1]Remaining effect of influenza vaccines received in prior seasons.[/h] Mart?nez-Baz I[SUP]1,[/SUP][SUP]2[/SUP], Navascu?s A[SUP]3[/SUP], Casado I[SUP]1,[/SUP][SUP]2[/SUP], Aguinaga A[SUP]3[/SUP], Ezpeleta C[SUP]3[/SUP], Castilla J[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] This study evaluates the remaining effect of influenza vaccines received in the 5 prior seasons. During 7 influenza seasons 8933 patients were enrolled and 47% were confirmed for influenza. As compared to unvaccinated individuals in the current and 5 prior seasons, vaccination was protective when the last dose had been received in the current season (40%; 95%CI, 32-47), and one (42%; 95%CI, 27-54), 2-3 (35%; 95%CI, 16-49) or 4-5 seasons before (31%; 95%CI, 4-51). This effect lasted less in the elderly and chronic patients. On average, several recent prior doses were as protective as current season vaccination.
? The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
[h=4]KEYWORDS:[/h] case-control study; influenza; influenza vaccine; repeated vaccination; test-negative study; vaccination history; vaccine effectiveness
PMID: 31107953 DOI: 10.1093/infdis/jiz266
[h=1]Remaining effect of influenza vaccines received in prior seasons.[/h] Mart?nez-Baz I[SUP]1,[/SUP][SUP]2[/SUP], Navascu?s A[SUP]3[/SUP], Casado I[SUP]1,[/SUP][SUP]2[/SUP], Aguinaga A[SUP]3[/SUP], Ezpeleta C[SUP]3[/SUP], Castilla J[SUP]1,[/SUP][SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] This study evaluates the remaining effect of influenza vaccines received in the 5 prior seasons. During 7 influenza seasons 8933 patients were enrolled and 47% were confirmed for influenza. As compared to unvaccinated individuals in the current and 5 prior seasons, vaccination was protective when the last dose had been received in the current season (40%; 95%CI, 32-47), and one (42%; 95%CI, 27-54), 2-3 (35%; 95%CI, 16-49) or 4-5 seasons before (31%; 95%CI, 4-51). This effect lasted less in the elderly and chronic patients. On average, several recent prior doses were as protective as current season vaccination.
? The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
[h=4]KEYWORDS:[/h] case-control study; influenza; influenza vaccine; repeated vaccination; test-negative study; vaccination history; vaccine effectiveness
PMID: 31107953 DOI: 10.1093/infdis/jiz266