Catbird
Senior Moderator
From: Infectious Disease News
"January 10, 2013
Perlin DS. J Clin Microbiol. 2013;doi:10.1128/JCM.03369-12
Researchers have developed a real-time assay for the rapid detection of Exserohilum rostratum, the mold pathogen largely responsible for the deadly outbreak of fungal meningitis associated with tainted vials of methylprednisolone. The real-time PCR assay is highly accurate and capable of detecting E. rostratum efficiently, according to study results.
?Fungal meningitis, like many acute life-threatening infections, requires a rapid identification of the source of disease to be able to manage it effectively,? David S. Perlin, PhD, executive director of the Public Health Research Institute at the University of Medicine and Dentistry of New Jersey, told Infectious Disease News.
The PCR assay uses molecular beacon technology, designed in this case to specifically detect E. rostratum.
...The new assay is applicable to detect E. rostratum in human tissue for rapid diagnosis and to monitor cerebrospinal fluid samples of infected patients receiving antifungal therapy. The new assay may also be used for E. rostratum detection in medication vials, which potentially could allow health officials and drug manufacturers to screen for the pathogen and prevent future outbreaks...".
"January 10, 2013
Perlin DS. J Clin Microbiol. 2013;doi:10.1128/JCM.03369-12
Researchers have developed a real-time assay for the rapid detection of Exserohilum rostratum, the mold pathogen largely responsible for the deadly outbreak of fungal meningitis associated with tainted vials of methylprednisolone. The real-time PCR assay is highly accurate and capable of detecting E. rostratum efficiently, according to study results.
?Fungal meningitis, like many acute life-threatening infections, requires a rapid identification of the source of disease to be able to manage it effectively,? David S. Perlin, PhD, executive director of the Public Health Research Institute at the University of Medicine and Dentistry of New Jersey, told Infectious Disease News.
The PCR assay uses molecular beacon technology, designed in this case to specifically detect E. rostratum.
...The new assay is applicable to detect E. rostratum in human tissue for rapid diagnosis and to monitor cerebrospinal fluid samples of infected patients receiving antifungal therapy. The new assay may also be used for E. rostratum detection in medication vials, which potentially could allow health officials and drug manufacturers to screen for the pathogen and prevent future outbreaks...".