tetano
Editor, Senior Moderator
J Infect Dis. 2012 Apr 23. [Epub ahead of print]
Rates of Hospitalizations for Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza Virus in Older Adults.
Widmer K, Zhu Y, Williams JV, Griffin MR, Edwards KM, Talbot HK.
Source
Vanderbilt University Medical Center Department of Medicine, VA TN Valley Health Care System, Nashville, TN.
Abstract
BackgroundWe performed a prospective study to determine the disease burden of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) in older adults in comparison to influenza virus.MethodsDuring three consecutive winters, we enrolled Davidson County (Nashville, TN) residents aged ≥50 years admitted to one of four hospitals with acute respiratory illness (ARI). Nasal/throat swabs were tested for influenza, RSV, and HMPV with reverse-transcriptase polymerase chain reaction (RT-PCR). Hospitalization rates were calculated.ResultsOf 1042 eligible patients, 508 consented to testing. RSV was detected in 31 participants (6.1%), HMPV in 23 (4.5%), and influenza in 33 (6.5%). Of those subjects aged ≥65 years, 78% received influenza vaccination. Compared to patients with confirmed influenza, patients with RSV were older and more immunocompromised; patients with HMPV were older, had more cardiovascular disease, were more likely to have received the influenza vaccination, and were less likely to report fever than those with influenza. Over three years, average annual rates of hospitalization were 15.01, 9.82, and 11.81 per 10,000 county residents due to RSV, HMPV, and influenza, respectively.ConclusionsIn adults ≥50 years old, hospitalization rates for RSV and HMPV were similar to those associated with influenza.
PMID:
22529314
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22529314
Rates of Hospitalizations for Respiratory Syncytial Virus, Human Metapneumovirus, and Influenza Virus in Older Adults.
Widmer K, Zhu Y, Williams JV, Griffin MR, Edwards KM, Talbot HK.
Source
Vanderbilt University Medical Center Department of Medicine, VA TN Valley Health Care System, Nashville, TN.
Abstract
BackgroundWe performed a prospective study to determine the disease burden of respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) in older adults in comparison to influenza virus.MethodsDuring three consecutive winters, we enrolled Davidson County (Nashville, TN) residents aged ≥50 years admitted to one of four hospitals with acute respiratory illness (ARI). Nasal/throat swabs were tested for influenza, RSV, and HMPV with reverse-transcriptase polymerase chain reaction (RT-PCR). Hospitalization rates were calculated.ResultsOf 1042 eligible patients, 508 consented to testing. RSV was detected in 31 participants (6.1%), HMPV in 23 (4.5%), and influenza in 33 (6.5%). Of those subjects aged ≥65 years, 78% received influenza vaccination. Compared to patients with confirmed influenza, patients with RSV were older and more immunocompromised; patients with HMPV were older, had more cardiovascular disease, were more likely to have received the influenza vaccination, and were less likely to report fever than those with influenza. Over three years, average annual rates of hospitalization were 15.01, 9.82, and 11.81 per 10,000 county residents due to RSV, HMPV, and influenza, respectively.ConclusionsIn adults ≥50 years old, hospitalization rates for RSV and HMPV were similar to those associated with influenza.
PMID:
22529314
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22529314