Prospective and retrospective evaluation of the Cepheid Xpert? Flu/RSV XC assay for rapid detection of influenza A, influenza B, and respiratory syncy

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Diagn Microbiol Infect Dis. 2015 Jan 24. pii: S0732-8893(15)00024-3. doi: 10.1016/j.diagmicrobio.2015.01.008. [Epub ahead of print]
[h=1]Prospective and retrospective evaluation of the Cepheid Xpert? Flu/RSV XC assay for rapid detection of influenza A, influenza B, and respiratory syncytial virus.[/h] Salez N[SUP]1[/SUP], Nougairede A[SUP]2[/SUP], Ninove L[SUP]2[/SUP], Zandotti C[SUP]2[/SUP], de Lamballerie X[SUP]2[/SUP], Charrel RN[SUP]2[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] A total of 281 clinical specimens (nasal swabs and nasopharyngeal aspirates) were tested with the Xpert? Flu/RSV XC. The results were compared to those obtained with the real-time retro transcriptase-polymerase chain reaction assays routinely used in our laboratory. The Xpert? Flu/RSV XC showed sensitivity/specificity of 97.8%/100% and 97.9%/100% for flu and respiratory syncytial virus, respectively.
Copyright ? 2015 Elsevier Inc. All rights reserved.


[h=4]KEYWORDS:[/h] Diagnosis; Flu; Point-of-care; RT-PCR; Rapid Influenza Detection Test; Real-time PCR; Syncytial respiratory virus

PMID: 25662018 [PubMed - as supplied by publisher]