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reprint describing other animals predisposed to covid 19 that can be carriers cows,pigs,sheep, pidgeons
Ye Qiu# , Yuan-Bo Zhao# , Qiong Wang, Jin-Yan Li, Zhi-Jian Zhou, Ce-Heng Liao, XingYi Ge*
Hunan Provincial Key Laboratory of Medical Virology, Institute of Pathogen Biology and Immunology, College of Biology, Hunan University, 27 Tianma Rd., Changsha, Hunan, 410012, China #
These authors contributed equally to this work. * Correspondence to Dr. Xing-Yi Ge Email: xyge@hnu.edu.cn Phone: 86-731-88822606 Address: 27 Tianma Rd, Changsha, Hunan, 410012, China
Abstract
SARS-CoV-2, the newly identified human coronavirus causing severe pneumonia epidemic, was probably originated from Chinese horseshoe bats. However, direct transmission of the virus from bats to humans is unlikely due to lack of direct contact, implying the existence of unknown intermediate hosts
Angiotensin converting enzyme 2 (ACE2) is the receptor of SARS-CoV-2, but only ACE2s of certain species can be utilized by SARS-CoV-2.
Here, we evaluated and ranked the receptor-utilizing capability of ACE2s from various species by phylogenetic clustering and sequence alignment with the currently known ACE2s utilized by SARS-CoV-2, predicting potential intermediate hosts of SARS-CoV-2. Keywords: SARS-CoV-2; coronavirus; :tiphat:file:///C:/Users/USER/Downloads/prep...03.0091.v1.pdf
reprint describing other animals predisposed to covid 19 that can be carriers cows,pigs,sheep, pidgeonsYe Qiu# , Yuan-Bo Zhao# , Qiong Wang, Jin-Yan Li, Zhi-Jian Zhou, Ce-Heng Liao, XingYi Ge*
Hunan Provincial Key Laboratory of Medical Virology, Institute of Pathogen Biology and Immunology, College of Biology, Hunan University, 27 Tianma Rd., Changsha, Hunan, 410012, China #
These authors contributed equally to this work. * Correspondence to Dr. Xing-Yi Ge Email: xyge@hnu.edu.cn Phone: 86-731-88822606 Address: 27 Tianma Rd, Changsha, Hunan, 410012, China
Abstract
SARS-CoV-2, the newly identified human coronavirus causing severe pneumonia epidemic, was probably originated from Chinese horseshoe bats. However, direct transmission of the virus from bats to humans is unlikely due to lack of direct contact, implying the existence of unknown intermediate hosts
Angiotensin converting enzyme 2 (ACE2) is the receptor of SARS-CoV-2, but only ACE2s of certain species can be utilized by SARS-CoV-2.
Here, we evaluated and ranked the receptor-utilizing capability of ACE2s from various species by phylogenetic clustering and sequence alignment with the currently known ACE2s utilized by SARS-CoV-2, predicting potential intermediate hosts of SARS-CoV-2. Keywords: SARS-CoV-2; coronavirus; :tiphat:file:///C:/Users/USER/Downloads/prep...03.0091.v1.pdf
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