tetano
Editor, Senior Moderator
[h=1]Potential Risks and Benefits of Gain-of-Function Research: Summary of a Workshop.[/h] [h=3]Editors[/h] Board on Life Sciences, Division on Earth and Life Studies; Committee on Science, Technology and Law, Policy and Global Affairs Division; Board on Health Sciences Policy; National Research Council; Institute of Medicine.
[h=3]Source[/h] Washington (DC): National Academies Press (US); 2015.
The National Academies Collection: Reports funded by National Institutes of Health.
[h=3]Excerpt[/h] On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.
Copyright ? 2015, National Academy of Sciences.
[h=3]Sections[/h]
PMID: 25719185 [PubMed] Free Books & DocumentsFree full text
[h=3]Source[/h] Washington (DC): National Academies Press (US); 2015.
The National Academies Collection: Reports funded by National Institutes of Health.
[h=3]Excerpt[/h] On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.
Copyright ? 2015, National Academy of Sciences.
[h=3]Sections[/h]
PMID: 25719185 [PubMed] Free Books & DocumentsFree full text