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Pneumonia in patients with novel influenza A (H1N1) virus in Southeastern Turkey

tetano

Editor, Senior Moderator
Wien Klin Wochenschr. 2011 Feb 16. [Epub ahead of print]
Pneumonia in patients with novel influenza A (H1N1) virus in Southeastern Turkey.

Ornek T, Yal?ın FD, Ekin S, Yal?ın S, Yemişen M.

Department of Pulmonology, Zonguldak Karaelmas University Medical Faculty, Zonguldak, Turkey, tacettinornek@yahoo.com.
Abstract

The objective of this study was to describe the clinical characteristics and the radiological and laboratory findings of the hospitalised patients who had novel, laboratory-confirmed, swine-origin influenza A virus (S-OIV) infection with pneumonia. Between October and December 2009, 56 patients hospitalised for pneumonia who were tested for S-OIV infection were retrospectively evaluated. Thirty-three patients had positive S-OIV infections. In addition, 23 of the 56 patients who had negative test results for S-OIV infection were compared with the positive group. The mortality rate amongst the patients with S-OIV infection was 24.2%. Of the 33 patients, 42.4% had at least one underlying medical condition and 4 (12%) patients were pregnant or postpartum. Fourteen patients (42.4%) with S-OIV infection were followed up in an intensive care unit. The most common symptom was dyspnea. The mean peak body temperature during hospital stay (39.42 ? 0.70) was higher in this group than in the negative group (38.51 ? 1.05) (p = 0.001). Thrombocytopenia, increased creatine kinase and elevated lactate dehydrogenase levels were statistically significant. Bilateral infiltration was more common in the patients with S-OIV infection. Although some laboratory, radiological and clinical data show a significant difference between the patients with S-OIV pneumonia and the negative group, each patient presenting with signs of pneumonia during pandemia should be tested for Influenza A.

PMID: 21318739 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/21318739
 
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